# Adrenoceptor alpha 2C

> mammalian protein found in Homo sapiens

**Wikidata**: [Q4734891](https://www.wikidata.org/wiki/Q4734891)  
**Source**: https://4ort.xyz/entity/adrenoceptor-alpha-2c-q4734891


## References

1. UniProt
2. IUPHAR/BPS Guide to PHARMACOLOGY
3. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL677)
4. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL679)
5. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL1437)
6. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL211456)
7. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL1200379)
8. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL1200833)
9. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL1200791)
10. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL1200787)
11. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL2106195)
12. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P18825)
13. Q20641742
14. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825)
15. [Delayed transactivation of the receptor for nerve growth factor is required for sustained signaling and differentiation by alpha2-adrenergic receptors in transfected PC12 cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825)
16. [Alpha2A- and alpha2C-adrenergic receptors form homo- and heterodimers: the heterodimeric state impairs agonist-promoted GRK phosphorylation and beta-arrestin recruitment](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825)
17. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18825&geneProductId=UniProtKB:P18825)
18. [Interaction of the amyloid precursor like protein 1 with the alpha2A-adrenergic receptor increases agonist-mediated inhibition of adenylate cyclase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825)
19. [Molecular cloning, sequencing and functional study of the promoter region of the human α2C4-adrenergic receptor gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825)
20. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825)
21. [Role of arrestins in endocytosis and signaling of alpha2-adrenergic receptor subtypes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825)
22. [Molecular cloning, sequencing and functional study of the promoter region of the human α2C4-adrenergic receptor gene](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18825&geneProductId=UniProtKB:P18825)
23. [Alpha2A- and alpha2C-adrenergic receptors form homo- and heterodimers: the heterodimeric state impairs agonist-promoted GRK phosphorylation and beta-arrestin recruitment](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18825&geneProductId=UniProtKB:P18825)
24. [Interaction of the ubiquitin carboxyl terminal esterase L1 with alpha(2)-adrenergic receptors inhibits agonist-mediated p44/42 MAP kinase activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825)
25. Ensembl Release 99