# ADP ribosylation factor 6

> mammalian protein found in Homo sapiens

**Wikidata**: [Q4653665](https://www.wikidata.org/wiki/Q4653665)  
**Source**: https://4ort.xyz/entity/adp-ribosylation-factor-6-q4653665


## References

1. UniProt
2. [BioGRID](https://thebiogrid.org/news/227)
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P62330)
4. Q20641742
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62330)
6. [Separation of Membrane Trafficking and Actin Remodeling Functions of ARF6 with an Effector Domain Mutant](http://www.ebi.ac.uk/QuickGO/annotations?protein=P62330&geneProductId=UniProtKB:P62330)
7. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P62330&geneProductId=UniProtKB:P62330)
8. [Rab11‐FIP3 and FIP4 interact with Arf6 and the Exocyst to control membrane traffic in cytokinesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62330)
9. [TBC1D24, an ARF6-Interacting Protein, Is Mutated in Familial Infantile Myoclonic Epilepsy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62330)
10. [A role for POR1, a Rac1‐interacting protein, in ARF6‐mediated cytoskeletal rearrangements](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62330)
11. [Sequential Cyk‐4 binding to ECT2 and FIP3 regulates cleavage furrow ingression and abscission during cytokinesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62330)
12. [Structural basis for Rab11-dependent membrane recruitment of a family of Rab11-interacting protein 3 (FIP3)/Arfophilin-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62330)
13. [The structural basis of Arf effector specificity: the crystal structure of ARF6 in a complex with JIP4](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62330)
14. [Structural basis for Arf6–MKLP1 complex formation on the Flemming body responsible for cytokinesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62330)
15. [V-ATPase interacts with ARNO and Arf6 in early endosomes and regulates the protein degradative pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62330)
16. [ARF6 GTPase protects the post‐mitotic midbody from 14‐3‐3‐mediated disintegration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62330)
17. [Molecular identification of ADP-ribosylation factor mRNAs and their expression in mammalian cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62330)
18. [The TBC (Tre-2/Bub2/Cdc16) Domain Protein TRE17 Regulates Plasma Membrane-Endosomal Trafficking through Activation of Arf6](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62330)
19. [Separation of Membrane Trafficking and Actin Remodeling Functions of ARF6 with an Effector Domain Mutant](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62330)
20. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62330)
21. [A Protein Interaction Network for Ecm29 Links the 26 S Proteasome to Molecular Motors and Endosomal Components](http://www.ebi.ac.uk/QuickGO/annotations?protein=P62330&geneProductId=UniProtKB:P62330)
22. [Intracellular Distribution of Arf Proteins in Mammalian Cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P62330&geneProductId=UniProtKB:P62330)
23. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P62330&geneProductId=UniProtKB:P62330)
24. [Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P62330&geneProductId=UniProtKB:P62330)
25. [A role for POR1, a Rac1‐interacting protein, in ARF6‐mediated cytoskeletal rearrangements](http://www.ebi.ac.uk/QuickGO/annotations?protein=P62330&geneProductId=UniProtKB:P62330)
26. [Intracellular Distribution of Arf Proteins in Mammalian Cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62330)
27. [The Arl4 Family of Small G Proteins Can Recruit the Cytohesin Arf6 Exchange Factors to the Plasma Membrane](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62330)
28. [AIP1 Functions as Arf6-GAP to Negatively Regulate TLR4 Signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62330)
29. [ARF6 requirement for Rac ruffling suggests a role for membrane trafficking in cortical actin rearrangements](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62330)
30. [AIP1 Functions as Arf6-GAP to Negatively Regulate TLR4 Signaling](http://www.ebi.ac.uk/QuickGO/annotations?protein=P62330&geneProductId=UniProtKB:P62330)
31. [Proteomic analysis of podocyte exosome-enriched fraction from normal human urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P62330&geneProductId=UniProtKB:P62330)
32. [In‐depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P62330&geneProductId=UniProtKB:P62330)
33. [MHC class II‐associated proteins in B‐cell exosomes and potential functional implications for exosome biogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P62330&geneProductId=UniProtKB:P62330)
34. [Regulation of Dendritic Branching and Filopodia Formation in Hippocampal Neurons by Specific Acylated Protein Motifs](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62330)
35. [MICAL‐L1 is a Tubular Endosomal Membrane Hub that Connects Rab35 and Arf6 With Rab8a](http://www.ebi.ac.uk/QuickGO/annotations?protein=P62330&geneProductId=UniProtKB:P62330)
36. [EFA6 activates Arf6 and participates in its targeting to the Flemming body during cytokinesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62330)
37. [A Protein Interaction Network for Ecm29 Links the 26 S Proteasome to Molecular Motors and Endosomal Components](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62330)
38. [Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62330)
39. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62330)
40. [MICAL‐L1 is a Tubular Endosomal Membrane Hub that Connects Rab35 and Arf6 With Rab8a](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62330)
41. [In‐depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62330)
42. [MHC class II‐associated proteins in B‐cell exosomes and potential functional implications for exosome biogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62330)
43. [ARF6 requirement for Rac ruffling suggests a role for membrane trafficking in cortical actin rearrangements](http://www.ebi.ac.uk/QuickGO/annotations?protein=P62330&geneProductId=UniProtKB:P62330)
44. [FRMD4A–cytohesin signaling modulates the cellular release of tau](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62330)
45. Ensembl Release 99
46. UMLS 2023