Adenylosuccinate synthase
type: Thing
description: mammalian protein found in Rattus norvegicus
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P352
  value: D4AEP0
additional property: PropertyValue
  property ID: P361
  value: Adenylosuccinate synthetase isozyme 2, chordates
additional property: PropertyValue
  property ID: P361
  value: P-loop containing nucleoside triphosphate hydrolase
additional property: PropertyValue
  property ID: P361
  value: Adenylosuccinate synthase, active site, protein family
additional property: PropertyValue
  property ID: P527
  value: Adenylosuccinate synthase, active site
additional property: PropertyValue
  property ID: P527
  value: Adenylosuccinate synthase, GTP-binding site
additional property: PropertyValue
  property ID: P637
  value: NP_001099445
additional property: PropertyValue
  property ID: P680
  value: nucleotide binding
additional property: PropertyValue
  property ID: P680
  value: magnesium ion binding
additional property: PropertyValue
  property ID: P680
  value: adenylosuccinate synthase activity
additional property: PropertyValue
  property ID: P681
  value: cytoplasm
additional property: PropertyValue
  property ID: P681
  value: cytosol
additional property: PropertyValue
  property ID: P681
  value: plasma membrane
additional property: PropertyValue
  property ID: P682
  value: purine nucleotide biosynthetic process
additional property: PropertyValue
  property ID: P682
  value: AMP biosynthetic process
additional property: PropertyValue
  property ID: P682
  value: aspartate metabolic process
additional property: PropertyValue
  property ID: P702
  value: Adss
additional property: PropertyValue
  property ID: P703
  value: brown rat
confidence:
  popularity graph score:
    score: 0.001
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 9
      unique citations norm: 0.004
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 9
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: D4AEP0
    source count: 1
    confidence: 0.2
  P361:
    value: Q24725377
    source count: 1
    confidence: 0.2
    value label: Adenylosuccinate synthetase isozyme 2, chordates
  P361:
    value: Q24726930
    source count: 1
    confidence: 0.2
    value label: P-loop containing nucleoside triphosphate hydrolase
  P361:
    value: Q95351393
    source count: 1
    confidence: 0.2
    value label: Adenylosuccinate synthase, active site, protein family
  P361:
    value: Q95353160
    source count: 1
    confidence: 0.2
    value label: Adenylosuccinate synthase, GTP-binding site, protein family
  P527:
    value: Q24740369
    source count: 1
    confidence: 0.2
    value label: Adenylosuccinate synthase, active site
  P527:
    value: Q24768659
    source count: 1
    confidence: 0.2
    value label: Adenylosuccinate synthase, GTP-binding site
  P637:
    value: NP_001099445
    source count: 1
    confidence: 0.2
  P680:
    value: Q14860365
    source count: 1
    confidence: 0.2
    value label: nucleotide binding
  P680:
    value: Q14860850
    source count: 1
    confidence: 0.2
    value label: magnesium ion binding
  P680:
    value: Q21122603
    source count: 5
    confidence: 1.0
    value label: adenylosuccinate synthase activity
  P680:
    value: Q14863341
    source count: 2
    confidence: 0.4
    value label: GTP binding
  P680:
    value: Q14861871
    source count: 1
    confidence: 0.2
    value label: ligase activity
  P681:
    value: Q79899
    source count: 3
    confidence: 0.6
    value label: cytoplasm
  P681:
    value: Q220599
    source count: 1
    confidence: 0.2
    value label: cytosol
  P681:
    value: Q29548
    source count: 1
    confidence: 0.2
    value label: plasma membrane
  P682:
    value: Q14864590
    source count: 3
    confidence: 0.6
    value label: purine nucleotide biosynthetic process
  P682:
    value: Q14914062
    source count: 2
    confidence: 0.4
    value label: AMP biosynthetic process
  P682:
    value: Q21116240
    source count: 1
    confidence: 0.2
    value label: aspartate metabolic process
  P682:
    value: Q21100447
    source count: 1
    confidence: 0.2
    value label: response to purine-containing compound
  P682:
    value: Q14914064
    source count: 2
    confidence: 0.4
    value label: 'de novo' AMP biosynthetic process
  P702:
    value: Q24379772
    source count: 1
    confidence: 0.2
    value label: Adss
  P703:
    value: Q184224
    source count: 1
    confidence: 0.2
    value label: brown rat
citations:
  source: GOA
  stated in qid: Q28018111
  retrieved: 2019-02-14
citations:
  source: Adenylosuccinate synthetase in rat liver: The existence of two types and their regulatory roles
  stated in qid: Q28574500
  retrieved: 2019-02-14

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2019-02-14

source: Changes in isozymes of adenylosuccinate synthetase
stated in qid: Q28579274
retrieved: 2019-02-14

source: Effect of acidosis and uninephrectomy on isozymes of adenylosuccinate synthetase in rat kidney
stated in qid: Q28577243
retrieved: 2019-02-14

source: Electrical stimulation of neonatal cardiac myocytes activates the NFAT3 and GATA4 pathways and up-regulates the adenylosuccinate synthetase 1 gene
stated in qid: Q28566172
retrieved: 2019-02-14

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2021-11-17

source: Q20641742
stated in qid: Q20641742
retrieved: 2021-09-07

wikidata id: Q29519853
domain: protein
level: standard
html url: https://4ort.xyz/entity/adenylosuccinate-synthase
markdown url: https://4ort.xyz/entity/adenylosuccinate-synthase.md
facts url summary: https://4ort.xyz/entity/adenylosuccinate-synthase/facts.json
facts url standard: https://4ort.xyz/entity/adenylosuccinate-synthase/facts.json
facts url full: https://4ort.xyz/entity/adenylosuccinate-synthase/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-24T12:34:07.716465Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T15:13:28.188618+00:00Z