# Adenylate cyclase activating polypeptide 1

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28557398](https://www.wikidata.org/wiki/Q28557398)  
**Source**: https://4ort.xyz/entity/adenylate-cyclase-activating-polypeptide-1-q28557398


## References

1. UniProt
2. Q20641742
3. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13589)
4. [Rapgef2 Connects GPCR-Mediated cAMP Signals to ERK Activation in Neuronal and Endocrine Cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13589)
5. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13589)
6. [VIP Induces the Translocation and Degradation of the Subunit of Gs Protein in Rat Pituitary GH4C1 Cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13589)
7. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P13589&geneProductId=UniProtKB:P13589)
8. [Structural characterization of PACAP receptors on rat liver plasma membranes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P13589&geneProductId=UniProtKB:P13589)
9. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P13589&geneProductId=UniProtKB:P13589)
10. [Structural characterization of PACAP receptors on rat liver plasma membranes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13589)
11. [Inhibitory effect of PACAP-38 on acute neurogenic and non-neurogenic inflammatory processes in the rat](http://www.ebi.ac.uk/QuickGO/annotations?protein=P13589&geneProductId=UniProtKB:P13589)
12. [Pituitary adenylate cyclase-activating polypeptide-nerve terminals densely innervate corticotropin-releasing hormone-neurons in the hypothalamic paraventricular nucleus of the rat](http://www.ebi.ac.uk/QuickGO/annotations?protein=P13589&geneProductId=UniProtKB:P13589)
13. [Inhibitory effect of PACAP-38 on acute neurogenic and non-neurogenic inflammatory processes in the rat](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13589)
14. [Pituitary adenylate cyclase-activating polypeptide-nerve terminals densely innervate corticotropin-releasing hormone-neurons in the hypothalamic paraventricular nucleus of the rat](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13589)
15. [Inhibitory effect of pituitary adenylate cyclase activating polypeptide on the initial stages of rat follicle development](http://www.ebi.ac.uk/QuickGO/annotations?protein=P13589&geneProductId=UniProtKB:P13589)
16. [Microinfusion of pituitary adenylate cyclase-activating polypeptide into the central nucleus of amygdala of the rat produces a shift from an active to passive mode of coping in the shock-probe fear/defensive burying test](http://www.ebi.ac.uk/QuickGO/annotations?protein=P13589&geneProductId=UniProtKB:P13589)
17. [Tachyphylaxis of the ECL-cell response to PACAP: receptor desensitization and/or depletion of secretory products](http://www.ebi.ac.uk/QuickGO/annotations?protein=P13589&geneProductId=UniProtKB:P13589)
18. [Pituitary adenylate cyclase-activating polypeptide 38-mediated Rin activation requires Src and contributes to the regulation of HSP27 signaling during neuronal differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13589)
19. [Effects of PACAP on mitochondrial apoptotic pathways and cytokine expression in rats subjected to renal ischemia/reperfusion](http://www.ebi.ac.uk/QuickGO/annotations?protein=P13589&geneProductId=UniProtKB:P13589)
20. [Selenoprotein T is a PACAP-regulated gene involved in intracellular Ca2+ mobilization and neuroendocrine secretion](http://www.ebi.ac.uk/QuickGO/annotations?protein=P13589&geneProductId=UniProtKB:P13589)
21. [Expression of pituitary adenylate cyclase-activating polypeptide and PACAP type 1 receptor in the rat gastric and colonic myenteric neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13589)
22. [PACAP regulation of secretion and proliferation of pure populations of gastric ECL cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P13589&geneProductId=UniProtKB:P13589)
23. [PACAP inhibits oxidative stress-induced activation of MAP kinase-dependent apoptotic pathway in cultured cardiomyocytes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P13589&geneProductId=UniProtKB:P13589)
24. [Pituitary adenylate cyclase-activating polypeptide 38-mediated Rin activation requires Src and contributes to the regulation of HSP27 signaling during neuronal differentiation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P13589&geneProductId=UniProtKB:P13589)
25. [Divergent peripheral effects of pituitary adenylate cyclase-activating polypeptide-38 on nociception in rats and mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=P13589&geneProductId=UniProtKB:P13589)
26. [Weaning and the developmental changes in follicle-stimulating hormone, pituitary adenylate cyclase-activating polypeptide, and inhibin B in the male rat](http://www.ebi.ac.uk/QuickGO/annotations?protein=P13589&geneProductId=UniProtKB:P13589)
27. [PACAP stimulates the release of interleukin-6 in cultured rat Müller cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P13589&geneProductId=UniProtKB:P13589)
28. [Pituitary adenylyl cyclase-activating polypeptide 38 reduces astroglial proliferation by inhibiting the GTPase RhoA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P13589&geneProductId=UniProtKB:P13589)
29. [Short-term fasting differentially alters PACAP and VIP levels in the brains of rat and chicken](http://www.ebi.ac.uk/QuickGO/annotations?protein=P13589&geneProductId=UniProtKB:P13589)
30. [Pituitary adenylate cyclase-activating polypeptide (PACAP) stimulates the oxygen sensing type I (glomus) cells of rat carotid bodies via reduction of a background TASK-like K+ current](http://www.ebi.ac.uk/QuickGO/annotations?protein=P13589&geneProductId=UniProtKB:P13589)
31. [Effects of PACAP, VIP and related peptides on cyclic AMP formation in rat neuronal and astrocyte cultures and cerebral cortical slices](http://www.ebi.ac.uk/QuickGO/annotations?protein=P13589&geneProductId=UniProtKB:P13589)
32. [Ethanol decreases the expression of pituitary adenylate cyclase activating polypeptide in rat testes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P13589&geneProductId=UniProtKB:P13589)
33. [PACAP-mediated ATP release from rat urothelium and regulation of PACAP/VIP and receptor mRNA in micturition pathways after cyclophosphamide (CYP)-induced cystitis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P13589&geneProductId=UniProtKB:P13589)
34. [Regulation of glutamatergic signalling by PACAP in the mammalian suprachiasmatic nucleus](http://www.ebi.ac.uk/QuickGO/annotations?protein=P13589&geneProductId=UniProtKB:P13589)
35. [Modulation of AMPA receptor-mediated ion current by pituitary adenylate cyclase-activating polypeptide (PACAP) in CA1 pyramidal neurons from rat hippocampus](http://www.ebi.ac.uk/QuickGO/annotations?protein=P13589&geneProductId=UniProtKB:P13589)
36. [Growth factor-dependent actions of PACAP on oligodendrocyte progenitor proliferation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P13589&geneProductId=UniProtKB:P13589)
37. [Changes of dopamine content and cell proliferation by dexamethsone via pituitary adenylate cyclase-activating polypeptide in PC12 cell](http://www.ebi.ac.uk/QuickGO/annotations?protein=P13589&geneProductId=UniProtKB:P13589)
38. [Temperature-sensitive phenotype in mice lacking pituitary adenylate cyclase-activating polypeptide](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13589)
39. [Inhibitory effect of pituitary adenylate cyclase activating polypeptide on the initial stages of rat follicle development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13589)
40. [Microinfusion of pituitary adenylate cyclase-activating polypeptide into the central nucleus of amygdala of the rat produces a shift from an active to passive mode of coping in the shock-probe fear/defensive burying test](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13589)
41. [Tachyphylaxis of the ECL-cell response to PACAP: receptor desensitization and/or depletion of secretory products](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13589)
42. [Effects of PACAP on mitochondrial apoptotic pathways and cytokine expression in rats subjected to renal ischemia/reperfusion](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13589)
43. [Selenoprotein T is a PACAP-regulated gene involved in intracellular Ca2+ mobilization and neuroendocrine secretion](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13589)
44. [PACAP regulation of secretion and proliferation of pure populations of gastric ECL cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13589)
45. [PACAP inhibits oxidative stress-induced activation of MAP kinase-dependent apoptotic pathway in cultured cardiomyocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13589)
46. [Divergent peripheral effects of pituitary adenylate cyclase-activating polypeptide-38 on nociception in rats and mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13589)
47. [Weaning and the developmental changes in follicle-stimulating hormone, pituitary adenylate cyclase-activating polypeptide, and inhibin B in the male rat](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13589)
48. [PACAP stimulates the release of interleukin-6 in cultured rat Müller cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13589)
49. [Pituitary adenylyl cyclase-activating polypeptide 38 reduces astroglial proliferation by inhibiting the GTPase RhoA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13589)
50. [Short-term fasting differentially alters PACAP and VIP levels in the brains of rat and chicken](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13589)