# Adenosine deaminase

> mammalian protein found in Mus musculus

**Wikidata**: [Q14864795](https://www.wikidata.org/wiki/Q14864795)  
**Source**: https://4ort.xyz/entity/adenosine-deaminase-q14864795


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P03958)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958)
5. [Probing the functional role of two conserved active site aspartates in mouse adenosine deaminase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958)
7. [Adenosine-dependent airway inflammation and hyperresponsiveness in partially adenosine deaminase-deficient mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958)
8. [Disruption of the adenosine deaminase gene causes hepatocellular impairment and perinatal lethality in mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958)
9. [Genetically engineered mice demonstrate that adenosine deaminase is essential for early postimplantation development](http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958)
10. [Adenosine deaminase-deficient mice generated using a two-stage genetic engineering strategy exhibit a combined immunodeficiency](http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958)
11. [Metabolic and immunologic consequences of limited adenosine deaminase expression in mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958)
12. [Probing the functional role of two conserved active site aspartates in mouse adenosine deaminase](http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958)
13. [Full genetic rescue of adenosine deaminase-deficient mice through introduction of the human gene](http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958)
14. [Chromosomal assignments of 23 biochemical loci of the rat by using rat x mouse somatic cell hybrids](http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958)
15. [Ontogeny of adenosine deaminase in the mouse decidua and placenta: immunolocalization and embryo transfer studies](http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958)
16. [Brain purines in a genetic mouse model of Lesch-Nyhan disease](http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958)
17. [Structural and functional analysis of the murine adenosine deaminase gene](http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958)
18. [Tissue-specific rescue suggests that placental adenosine deaminase is important for fetal development in mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958)
19. [5' flanking sequences of the murine adenosine deaminase gene direct expression of a reporter gene to specific prenatal and postnatal tissues in transgenic mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958)
20. [Adenosine deaminase-deficient mice generated using a two-stage genetic engineering strategy exhibit a combined immunodeficiency](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958)
21. [Disruption of the adenosine deaminase gene causes hepatocellular impairment and perinatal lethality in mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958)
22. [Genetically engineered mice demonstrate that adenosine deaminase is essential for early postimplantation development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958)
23. [Adenosine-dependent airway inflammation and hyperresponsiveness in partially adenosine deaminase-deficient mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958)
24. [Metabolic and immunologic consequences of limited adenosine deaminase expression in mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958)
25. [Brain purines in a genetic mouse model of Lesch-Nyhan disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958)
26. [Full genetic rescue of adenosine deaminase-deficient mice through introduction of the human gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958)
27. [Chromosomal assignments of 23 biochemical loci of the rat by using rat x mouse somatic cell hybrids](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958)
28. [Tissue-specific rescue suggests that placental adenosine deaminase is important for fetal development in mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958)
29. [Ontogeny of adenosine deaminase in the mouse decidua and placenta: immunolocalization and embryo transfer studies](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958)
30. [5' flanking sequences of the murine adenosine deaminase gene direct expression of a reporter gene to specific prenatal and postnatal tissues in transgenic mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958)
31. [Structural and functional analysis of the murine adenosine deaminase gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958)
32. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958)
33. [Long-term in vivo expression of a murine adenosine deaminase gene in rhesus monkey hematopoietic cells of multiple lineages after retroviral mediated gene transfer into CD34+ bone marrow cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958)
34. [Transcription factor gene AP-2 gamma essential for early murine development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958)
35. [Excess adenosine in murine penile erectile tissues contributes to priapism via A2B adenosine receptor signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958)
36. [Adenosine–deaminase–deficient mice die perinatally and exhibit liver–cell degeneration, atelectasis and small intestinal cell death](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958)
37. [Adenosine kinase inhibition promotes survival of fetal adenosine deaminase-deficient thymocytes by blocking dATP accumulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958)
38. [Further differentiation of murine double-positive thymocytes is inhibited in adenosine deaminase-deficient murine fetal thymic organ culture](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958)
39. [Metabolites from apoptotic thymocytes inhibit thymopoiesis in adenosine deaminase-deficient fetal thymic organ cultures](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958)
40. [Activation of apoptosis in early mouse embryos by 2'-deoxyadenosine exposure](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958)
41. [Adenosine deaminase deficiency increases thymic apoptosis and causes defective T cell receptor signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958)
42. [Function of murine adenosine deaminase in the gastrointestinal tract](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958)
43. [Impaired Germinal Center Maturation in Adenosine Deaminase Deficiency](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958)
44. [Effects of adenosine deaminase and A1 receptor deficiency in normoxic and ischaemic mouse hearts](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958)
45. [Metabolic consequences of adenosine deaminase deficiency in mice are associated with defects in alveogenesis, pulmonary inflammation, and airway obstruction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958)
46. [A(2A) receptor dependent and A(2A) receptor independent effects of extracellular adenosine on murine thymocytes in conditions of adenosine deaminase deficiency](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958)
47. [A protective role for the A1 adenosine receptor in adenosine-dependent pulmonary injury](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958)
48. [A3 adenosine receptor signaling contributes to airway inflammation and mucus production in adenosine deaminase-deficient mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958)
49. [Genetic removal of the A2A adenosine receptor enhances pulmonary inflammation, mucin production, and angiogenesis in adenosine deaminase-deficient mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03958)
50. [Function of murine adenosine deaminase in the gastrointestinal tract](http://www.ebi.ac.uk/QuickGO/annotations?protein=P03958&geneProductId=UniProtKB:P03958)