# Adenosine A2a receptor

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21116162](https://www.wikidata.org/wiki/Q21116162)  
**Source**: https://4ort.xyz/entity/adenosine-a2a-receptor


## References

1. UniProt
2. IUPHAR/BPS Guide to PHARMACOLOGY
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P29274)
4. Q20641742
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29274)
6. [Structure of an agonist-bound human A2A adenosine receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29274)
7. [Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29274)
8. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P29274&geneProductId=UniProtKB:P29274)
9. [The de-ubiquitinating enzyme Unp interacts with the retinoblastoma protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29274)
10. [Synergistic interaction between adenosine A2A and glutamate mGlu5 receptors: implications for striatal neuronal function.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29274)
11. [Interactions between calmodulin, adenosine A2A, and dopamine D2 receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29274)
12. [Systematic protein-protein interaction mapping for clinically relevant human GPCRs](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29274)
13. [The neuronal Ca(2+) -binding protein 2 (NECAB2) interacts with the adenosine A(2A) receptor and modulates the cell surface expression and function of the receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29274)
14. [The ubiquitin-specific protease Usp4 regulates the cell surface level of the A2A receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29274)
15. [Heterotrimeric G protein-independent signaling of a G protein-coupled receptor. Direct binding of ARNO/cytohesin-2 to the carboxyl terminus of the A2A adenosine receptor is necessary for sustained activation of the ERK/MAP kinase pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29274)
16. [The association of metabotropic glutamate receptor type 5 with the neuronal Ca2+-binding protein 2 modulates receptor function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29274)
17. [Presynaptic control of striatal glutamatergic neurotransmission by adenosine A1-A2A receptor heteromers](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29274)
18. [Adenosine A(2A) receptors assemble into higher-order oligomers at the plasma membrane](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29274)
19. [Detection of higher-order G protein-coupled receptor oligomers by a combined BRET-BiFC technique](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29274)
20. [Patterns of A2A extracellular adenosine receptor expression in different functional subsets of human peripheral T cells. Flow cytometry studies with anti-A2A receptor monoclonal antibodies](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29274)
21. [Hydrophilic side chains in the third and seventh transmembrane helical domains of human A2A adenosine receptors are required for ligand recognition](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29274)
22. [Dose and time effects of caffeine intake on human platelet adenosine A(2A) receptors : functional and biochemical aspects](http://www.ebi.ac.uk/QuickGO/annotations?protein=P29274&geneProductId=UniProtKB:P29274)
23. [Aggressiveness, hypoalgesia and high blood pressure in mice lacking the adenosine A2a receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29274)
24. [Dose and time effects of caffeine intake on human platelet adenosine A(2A) receptors : functional and biochemical aspects](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29274)
25. [Adenosine stimulates DNA fragmentation in human thymocytes by Ca(2+)-mediated mechanisms](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29274)
26. [Multivariate analysis of associations of 42 genes in ADHD, ODD and conduct disorder](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29274)
27. [Human mononuclear phagocytes express adenosine A1 receptors. A novel mechanism for differential regulation of Fc gamma receptor function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29274)
28. Ensembl Release 99
29. Transporter Classification database