# Activin receptor IIB

> mammalian protein found in Mus musculus

**Wikidata**: [Q14905181](https://www.wikidata.org/wiki/Q14905181)  
**Source**: https://4ort.xyz/entity/activin-receptor-iib


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P27040)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27040)
5. [Isolation and characterization of activin receptor from mouse embryonal carcinoma cells. Identification of its serine/threonine/tyrosine protein kinase activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27040)
6. [RLP, a novel Ras-like protein, is an immediate-early transforming growth factor-beta (TGF-beta) target gene that negatively regulates transcriptional activity induced by TGF-beta](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27040)
7. [Growth differentiation factor 11 signals through the transforming growth factor-beta receptor ALK5 to regionalize the anterior-posterior axis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27040)
8. [Regulation of endocytosis of activin type II receptors by a novel PDZ protein through Ral/Ral-binding protein 1-dependent pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27040)
9. [Lefty blocks a subset of TGFbeta signals by antagonizing EGF-CFC coreceptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27040)
10. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27040&geneProductId=UniProtKB:P27040)
11. [Regulation of myostatin activity and muscle growth](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27040&geneProductId=UniProtKB:P27040)
12. [Activin type IIA and IIB receptors mediate Gdf11 signaling in axial vertebral patterning](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27040&geneProductId=UniProtKB:P27040)
13. [Novel activin receptors: distinct genes and alternative mRNA splicing generate a repertoire of serine/threonine kinase receptors](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27040&geneProductId=UniProtKB:P27040)
14. [Isolation and characterization of activin receptor from mouse embryonal carcinoma cells. Identification of its serine/threonine/tyrosine protein kinase activity](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27040&geneProductId=UniProtKB:P27040)
15. [A flexible activin explains the membrane-dependent cooperative assembly of TGF-beta family receptors](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27040&geneProductId=UniProtKB:P27040)
16. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27040)
17. [Regulation of myostatin activity and muscle growth](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27040)
18. [Activin type IIA and IIB receptors mediate Gdf11 signaling in axial vertebral patterning](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27040)
19. [Novel activin receptors: distinct genes and alternative mRNA splicing generate a repertoire of serine/threonine kinase receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27040)
20. [A flexible activin explains the membrane-dependent cooperative assembly of TGF-beta family receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27040)
21. [Regulation of GDF-11 and myostatin activity by GASP-1 and GASP-2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27040)
22. [Genetic interactions between activin type IIB receptor and Smad2 genes in asymmetrical patterning of the thoracic organs and the development of pancreas islets](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27040&geneProductId=UniProtKB:P27040)
23. [The type II activin receptors are essential for egg cylinder growth, gastrulation, and rostral head development in mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27040)
24. [ALK1 signaling regulates early postnatal lymphatic vessel development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27040)
25. [The signaling pathway mediated by the type IIB activin receptor controls axial patterning and lateral asymmetry in the mouse](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27040)
26. [Generation of activin receptor type IIB isoform-specific hypomorphic alleles](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27040)
27. [B-cell translocation gene 2 (Btg2) regulates vertebral patterning by modulating bone morphogenetic protein/smad signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27040)
28. [Genetic interactions between activin type IIB receptor and Smad2 genes in asymmetrical patterning of the thoracic organs and the development of pancreas islets](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27040)
29. [Distinct and cooperative roles of mammalian Vg1 homologs GDF1 and GDF3 during early embryonic development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27040)
30. [Epithelial and ectomesenchymal role of the type I TGF-beta receptor ALK5 during facial morphogenesis and palatal fusion](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27040)
31. [Regulation of muscle growth by multiple ligands signaling through activin type II receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27040)
32. [The role of effectors of the activin signalling pathway, activin receptors IIA and IIB, and Smad2, in patterning of tooth development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27040)
33. [Activin receptor patterning of foregut organogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27040)
34. [Blockade of the activin receptor IIb activates functional brown adipogenesis and thermogenesis by inducing mitochondrial oxidative metabolism](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27040)
35. ensembl Release 106