# Activin A receptor, type 1

> mammalian protein found in Mus musculus

**Wikidata**: [Q14905144](https://www.wikidata.org/wiki/Q14905144)  
**Source**: https://4ort.xyz/entity/activin-a-receptor-type-1-q14905144


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P37172)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37172)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P37172&geneProductId=UniProtKB:P37172)
6. [The serine/threonine transmembrane receptor ALK2 mediates Müllerian inhibiting substance signaling](http://www.ebi.ac.uk/QuickGO/annotations?protein=P37172&geneProductId=UniProtKB:P37172)
7. [Cloning of a type I TGF-beta receptor and its effect on TGF-beta binding to the type II receptor](http://www.ebi.ac.uk/QuickGO/annotations?protein=P37172&geneProductId=UniProtKB:P37172)
8. [Expression cloning of an activin receptor, a predicted transmembrane serine kinase](http://www.ebi.ac.uk/QuickGO/annotations?protein=P37172&geneProductId=UniProtKB:P37172)
9. [Expression of type I and type IB receptors for activin in midgestation mouse embryos suggests distinct functions in organogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P37172&geneProductId=UniProtKB:P37172)
10. [RLP, a novel Ras-like protein, is an immediate-early transforming growth factor-beta (TGF-beta) target gene that negatively regulates transcriptional activity induced by TGF-beta](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37172)
11. [The novel type I serine-threonine kinase receptor Alk8 binds TGF-beta in the presence of TGF-betaRII](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37172)
12. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37172)
13. [Cloning of a type I TGF-beta receptor and its effect on TGF-beta binding to the type II receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37172)
14. [The serine/threonine transmembrane receptor ALK2 mediates Müllerian inhibiting substance signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37172)
15. [Expression cloning of an activin receptor, a predicted transmembrane serine kinase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37172)
16. [Expression of type I and type IB receptors for activin in midgestation mouse embryos suggests distinct functions in organogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37172)
17. [The ActR-I activin receptor protein is expressed in notochord, lens placode and pituitary primordium cells in the mouse embryo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37172)
18. [Notch1 regulates maturation of CD4+ and CD8+ thymocytes by modulating TCR signal strength](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37172)
19. [BMP signaling mediated by ALK2 in the visceral endoderm is necessary for the generation of primordial germ cells in the mouse embryo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37172)
20. [Multiple roles for activin-like kinase-2 signaling during mouse embryogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37172)
21. [BMP type I receptor ALK2 is essential for proper patterning at late gastrulation during mouse embryogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37172)
22. [Tgf-beta3-induced palatal fusion is mediated by Alk-5/Smad pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37172)
23. [Craniofacial defects in mice lacking BMP type I receptor Alk2 in neural crest cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37172)
24. [Defective ALK5 signaling in the neural crest leads to increased postmigratory neural crest cell apoptosis and severe outflow tract defects](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37172)
25. [Cardiac outflow tract defects in mice lacking ALK2 in neural crest cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P37172&geneProductId=UniProtKB:P37172)
26. [Defective ALK5 signaling in the neural crest leads to increased postmigratory neural crest cell apoptosis and severe outflow tract defects](http://www.ebi.ac.uk/QuickGO/annotations?protein=P37172&geneProductId=UniProtKB:P37172)
27. [Atrioventricular cushion transformation is mediated by ALK2 in the developing mouse heart](http://www.ebi.ac.uk/QuickGO/annotations?protein=P37172&geneProductId=UniProtKB:P37172)
28. [BMP signaling through ACVRI is required for left-right patterning in the early mouse embryo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37172)
29. [Activation of bone morphogenetic protein/Smad signaling in bronchial epithelial cells during airway inflammation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37172)
30. [The type I serine/threonine kinase receptor ActRIA (ALK2) is required for gastrulation of the mouse embryo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37172)
31. [Cardiac outflow tract defects in mice lacking ALK2 in neural crest cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37172)
32. [The novel type I serine-threonine kinase receptor Alk8 binds TGF-beta in the presence of TGF-betaRII](http://www.ebi.ac.uk/QuickGO/annotations?protein=P37172&geneProductId=UniProtKB:P37172)
33. [Atrioventricular cushion transformation is mediated by ALK2 in the developing mouse heart](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37172)
34. ensembl Release 106