# Activation of the ISR mediates the behavioral and neurophysiological abnormalities in Down syndrome

> Research article (Science, 2019) · cited 185× · AI/ML

**Wikidata**: [openalex:W2984765289](https://www.wikidata.org/wiki/openalex:W2984765289)  
**Source**: https://4ort.xyz/entity/activation-of-the-isr-mediates-the-behavioral-and-neurophysiological-abnormalities-in-down-syndrome