Activating transcription factor 6
type: Thing
description: mammalian protein found in Mus musculus
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P352
  value: F6VAN0
additional property: PropertyValue
  property ID: P361
  value: cAMP-dependent transcription factor ATF-6 alpha
additional property: PropertyValue
  property ID: P361
  value: membrane protein
additional property: PropertyValue
  property ID: P361
  value: Basic-leucine zipper domain, protein family
additional property: PropertyValue
  property ID: P527
  value: Basic-leucine zipper domain
additional property: PropertyValue
  property ID: P637
  value: NP_001074773
additional property: PropertyValue
  property ID: P637
  value: XP_006496855
additional property: PropertyValue
  property ID: P637
  value: XP_011237098
additional property: PropertyValue
  property ID: P680
  value: DNA binding
additional property: PropertyValue
  property ID: P680
  value: RNA polymerase II transcription regulatory region sequence-specific DNA binding
additional property: PropertyValue
  property ID: P680
  value: DNA-binding transcription factor activity
additional property: PropertyValue
  property ID: P681
  value: integral component of membrane
additional property: PropertyValue
  property ID: P681
  value: Golgi apparatus
additional property: PropertyValue
  property ID: P681
  value: endoplasmic reticulum membrane
additional property: PropertyValue
  property ID: P682
  value: regulation of transcription, DNA-templated
additional property: PropertyValue
  property ID: P682
  value: positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
additional property: PropertyValue
  property ID: P682
  value: transcription, DNA-templated
additional property: PropertyValue
  property ID: P702
  value: Atf6
additional property: PropertyValue
  property ID: P703
  value: house mouse
additional property: PropertyValue
  property ID: P705
  value: ENSMUSP00000027974
confidence:
  popularity graph score:
    score: 0.001
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 10
      unique citations norm: 0.004
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 10
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: F6VAN0
    source count: 1
    confidence: 0.2
  P361:
    value: Q24769165
    source count: 1
    confidence: 0.2
    value label: cAMP-dependent transcription factor ATF-6 alpha
  P361:
    value: Q423042
    source count: 1
    confidence: 0.2
    value label: membrane protein
  P361:
    value: Q83163863
    source count: 1
    confidence: 0.2
    value label: Basic-leucine zipper domain, protein family
  P527:
    value: Q24784063
    source count: 1
    confidence: 0.2
    value label: Basic-leucine zipper domain
  P637:
    value: NP_001074773
    source count: 1
    confidence: 0.2
  P637:
    value: XP_006496855
    source count: 1
    confidence: 0.2
  P637:
    value: XP_011237098
    source count: 1
    confidence: 0.2
  P637:
    value: XP_030109280
    source count: 1
    confidence: 0.2
  P680:
    value: Q14633858
    source count: 1
    confidence: 0.2
    value label: DNA binding
  P680:
    value: Q14864823
    source count: 3
    confidence: 0.6
    value label: RNA polymerase II transcription regulatory region sequence-specific DNA binding
  P680:
    value: Q14817979
    source count: 3
    confidence: 0.6
    value label: DNA-binding transcription factor activity
  P680:
    value: Q167149
    source count: 3
    confidence: 0.6
    value label: protein binding
  P680:
    value: Q14762994
    source count: 2
    confidence: 0.4
    value label: identical protein binding
  P681:
    value: Q14327652
    source count: 1
    confidence: 0.2
    value label: integral component of membrane
  P681:
    value: Q83181
    source count: 2
    confidence: 0.4
    value label: Golgi apparatus
  P681:
    value: Q14329032
    source count: 2
    confidence: 0.4
    value label: endoplasmic reticulum membrane
  P681:
    value: Q14349455
    source count: 3
    confidence: 0.6
    value label: membrane
  P681:
    value: Q14905112
    source count: 2
    confidence: 0.4
    value label: integral component of endoplasmic reticulum membrane
  P682:
    value: Q14633883
    source count: 1
    confidence: 0.2
    value label: regulation of transcription, DNA-templated
  P682:
    value: Q21109197
    source count: 2
    confidence: 0.4
    value label: positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
  P682:
    value: Q14763010
    source count: 1
    confidence: 0.2
    value label: transcription, DNA-templated
  P682:
    value: Q14633900
    source count: 1
    confidence: 0.2
    value label: endoplasmic reticulum unfolded protein response
  P682:
    value: Q14864261
    source count: 1
    confidence: 0.2
    value label: response to unfolded protein

value: Q18297439
source count: 1
confidence: 0.2
value label: Atf6

value: Q83310
source count: 1
confidence: 0.2
value label: house mouse

value: ENSMUSP00000027974
source count: 1
confidence: 0.2

source: GOA
stated in qid: Q28018111
retrieved: 2019-02-14

source: A thrombospondin-dependent pathway for a protective ER stress response
stated in qid: Q24337738
retrieved: 2019-02-14

source: The CREB coactivator CRTC2 links hepatic ER stress and fasting gluconeogenesis
stated in qid: Q41791624
retrieved: 2019-02-14

source: XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response
stated in qid: Q28585314
retrieved: 2019-02-14

source: GOA
stated in qid: Q28018111
retrieved: 2018-04-24

source: CRELD2 is a novel endoplasmic reticulum stress-inducible gene
stated in qid: Q28593939
retrieved: 2019-02-14

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2022-05-25

source: Q20641742
stated in qid: Q20641742
retrieved: 2022-03-20

source: ensembl Release 106
stated in qid: Q111699881

wikidata id: Q21981485
domain: protein
level: standard
html url: https://4ort.xyz/entity/activating-transcription-factor-6
markdown url: https://4ort.xyz/entity/activating-transcription-factor-6.md
facts url summary: https://4ort.xyz/entity/activating-transcription-factor-6/facts.json
facts url standard: https://4ort.xyz/entity/activating-transcription-factor-6/facts.json
facts url full: https://4ort.xyz/entity/activating-transcription-factor-6/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-24T03:58:01.992006Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T13:47:33.893913+00:00Z