# Activating transcription factor 2

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21116768](https://www.wikidata.org/wiki/Q21116768)  
**Source**: https://4ort.xyz/entity/activating-transcription-factor-2-q21116768


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P15336)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336)
5. [cJun modulates Ggamma-globin gene expression via an upstream cAMP response element](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336)
6. [Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA-binding heterodimers](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336)
7. [CREB proteins function as positive regulators of the translocated bcl-2 allele in t(14;18) lymphomas](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336)
8. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15336&geneProductId=UniProtKB:P15336)
9. [cJun modulates Ggamma-globin gene expression via an upstream cAMP response element](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15336&geneProductId=UniProtKB:P15336)
10. [Leucine zipper structure of the protein CRE-BP1 binding to the cyclic AMP response element in brain](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15336&geneProductId=UniProtKB:P15336)
11. [Characterization of Functional Domains of an Embryonic Stem Cell Coactivator UTF1 Which Are Conserved and Essential for Potentiation of ATF-2 Activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336)
12. [ATM-dependent phosphorylation of ATF2 is required for the DNA damage response](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336)
13. [Regulation of TIP60 by ATF2 modulates ATM activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336)
14. [Isolation and characterization of a novel member of the gene family encoding the cAMP response element-binding protein CRE-BP1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336)
15. [Mutual regulation of c-Jun and ATF2 by transcriptional activation and subcellular localization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336)
16. [In situ proximity ligation detection of c-Jun/AP-1 dimers reveals increased levels of c-Jun/Fra1 complexes in aggressive breast cancer cell lines in vitro and in vivo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336)
17. [JNK-ATF-2 inhibits thrombomodulin (TM) expression by recruiting histone deacetylase4 (HDAC4) and forming a transcriptional repression complex in the TM promoter](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336)
18. [Deconstruction of the SS18-SSX fusion oncoprotein complex: insights into disease etiology and therapeutics](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336)
19. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336)
20. [The palmitoyl acyltransferase HIP14 shares a high proportion of interactors with huntingtin: implications for a role in the pathogenesis of Huntington's disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336)
21. [Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336)
22. [A Comprehensive Resource of Interacting Protein Regions for Refining Human Transcription Factor Networks](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336)
23. [The N-terminal transactivation domain of ATF2 is a target for the co-operative activation of the c-jun promoter by p300 and 12S E1A](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336)
24. [Identification of bZIP interaction partners of viral proteins HBZ, MEQ, BZLF1, and K-bZIP using coiled-coil arrays](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336)
25. [Human vaccinia-related kinase 1 (VRK1) activates the ATF2 transcriptional activity by novel phosphorylation on Thr-73 and Ser-62 and cooperates with JNK](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336)
26. [Multiple cDNA clones encoding nuclear proteins that bind to the tax-dependent enhancer of HTLV-1: all contain a leucine zipper structure and basic amino acid domain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336)
27. [Hyperosmotic stress-induced ATF-2 activation through Polo-like kinase 3 in human corneal epithelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336)
28. [ATF-2 has intrinsic histone acetyltransferase activity which is modulated by phosphorylation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15336&geneProductId=UniProtKB:P15336)
29. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15336&geneProductId=UniProtKB:P15336)
30. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336)
31. [IRF2-binding protein-1 is a JDP2 ubiquitin ligase and an inhibitor of ATF2-dependent transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336)
32. [PKCε promotes oncogenic functions of ATF2 in the nucleus while blocking its apoptotic function at mitochondria](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336)
33. [ATF-2 has intrinsic histone acetyltransferase activity which is modulated by phosphorylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336)
34. [ATF5 increases cisplatin-induced apoptosis through up-regulation of cyclin D3 transcription in HeLa cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336)
35. [MicroRNA-204 is required for differentiation of human-derived cardiomyocyte progenitor cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336)
36. [MicroRNA-30b controls endothelial cell capillary morphogenesis through regulation of transforming growth factor beta 2.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336)
37. Ensembl Release 99
38. UMLS 2023