# Actinin alpha 3

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21096435](https://www.wikidata.org/wiki/Q21096435)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/Alpha-actinin-3)  
**Source**: https://4ort.xyz/entity/actinin-alpha-3


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q08043)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08043)
5. [Synaptopodin regulates the actin-bundling activity of alpha-actinin in an isoform-specific manner](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08043)
6. [Cell membrane expression of cardiac sodium channel Na(v)1.5 is modulated by alpha-actinin-2 interaction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08043)
7. [Activation of human neutrophils induces an interaction between the integrin beta 2-subunit (CD18) and the actin binding protein alpha-actinin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08043)
8. [Myozenin: an alpha-actinin- and gamma-filamin-binding protein of skeletal muscle Z lines](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08043)
9. [Myopalladin, a novel 145-kilodalton sarcomeric protein with multiple roles in Z-disc and I-band protein assemblies](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08043)
10. [Cloning and characterization of two human skeletal muscle alpha-actinin genes located on chromosomes 1 and 11](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08043)
11. [Alpha-actinin and vinculin in human neutrophils: reorganization during adhesion and relation to the actin network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08043)
12. [Disruption of alpha-actinin-integrin interactions at focal adhesions renders osteoblasts susceptible to apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08043)
13. [α-Actinin-3 deficiency is associated with reduced bone mass in human and mouse](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08043&geneProductId=UniProtKB:Q08043)
14. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08043&geneProductId=UniProtKB:Q08043)
15. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08043)
16. [Altered Ca2+ kinetics associated with α-actinin-3 deficiency may explain positive selection for ACTN3 null allele in human evolution](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08043)
17. Ensembl Release 99
18. [Identifiers.org](https://registry.identifiers.org/registry/uniprot)