# Actinin alpha 3

> mammalian protein found in Mus musculus

**Wikidata**: [Q21491079](https://www.wikidata.org/wiki/Q21491079)  
**Source**: https://4ort.xyz/entity/actinin-alpha-3-q21491079


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O88990)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88990)
5. [Molecular diversity of myofibrillar proteins: gene regulation and functional significance](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88990)
6. [Synaptopodin regulates the actin-bundling activity of alpha-actinin in an isoform-specific manner](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88990)
7. [Calsarcins, a novel family of sarcomeric calcineurin-binding proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88990)
8. [The Alström syndrome protein, ALMS1, interacts with α-actinin and components of the endosome recycling pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88990)
9. [Phosphorylation of mouse LASP-1 on threonine 156 by cAMP- and cGMP-dependent protein kinase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88990)
10. [A new role for the architecture of microvillar actin bundles in apical retention of membrane proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88990)
11. [α-Actinin-3 deficiency is associated with reduced bone mass in human and mouse](http://www.ebi.ac.uk/QuickGO/annotations?protein=O88990&geneProductId=UniProtKB:O88990)
12. [Tropomodulin isoforms regulate thin filament pointed-end capping and skeletal muscle physiology](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88990)
13. [CHAP is a newly identified Z-disc protein essential for heart and skeletal muscle function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88990)
14. [A cardiomyocyte-specific Wdr1 knockout demonstrates essential functional roles for actin disassembly during myocardial growth and maintenance in mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88990)
15. [Role of p90 ribosomal S6 kinase-mediated prorenin-converting enzyme in ischemic and diabetic myocardium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88990)
16. [An Actn3 knockout mouse provides mechanistic insights into the association between alpha-actinin-3 deficiency and human athletic performance](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88990)
17. [α-Actinin-3 deficiency alters muscle adaptation in response to denervation and immobilization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88990)
18. [Loss of ACTN3 gene function alters mouse muscle metabolism and shows evidence of positive selection in humans](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88990)
19. [α-Actinin-3 deficiency is associated with reduced bone mass in human and mouse](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88990)
20. [Altered Ca2+ kinetics associated with α-actinin-3 deficiency may explain positive selection for ACTN3 null allele in human evolution](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88990)
21. ensembl Release 106