# Actin alpha cardiac muscle 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21096423](https://www.wikidata.org/wiki/Q21096423)  
**Source**: https://4ort.xyz/entity/actin-alpha-cardiac-muscle-1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P68032)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P68032)
5. [Functional consequences of a mutation in an expressed human alpha-cardiac actin at a site implicated in familial hypertrophic cardiomyopathy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P68032)
6. [Human actin mutations associated with hypertrophic and dilated cardiomyopathies demonstrate distinct thin filament regulatory properties in vitro](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P68032)
7. [Overexpression of cardiac actin with baculovirus is promoter dependent](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P68032)
8. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P68032)
9. [Reduced ACTC1 Expression Might Play a Role in the Onset of Congenital Heart Disease by Inducing Cardiomyocyte Apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P68032)
10. [Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability](http://www.ebi.ac.uk/QuickGO/annotations?protein=P68032&geneProductId=UniProtKB:P68032)
11. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P68032&geneProductId=UniProtKB:P68032)
12. [Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P68032&geneProductId=UniProtKB:P68032)
13. [Defining alpha-skeletal and alpha-cardiac actin expression in human heart and skeletal muscle explains the absence of cardiac involvement in ACTA1 nemaline myopathy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P68032)
14. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P68032&geneProductId=UniProtKB:P68032)
15. [Protein profile of exosomes from trabecular meshwork cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P68032&geneProductId=UniProtKB:P68032)
16. [Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach](http://www.ebi.ac.uk/QuickGO/annotations?protein=P68032&geneProductId=UniProtKB:P68032)
17. [Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy](http://www.ebi.ac.uk/QuickGO/annotations?protein=P68032&geneProductId=UniProtKB:P68032)
18. [Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P68032)
19. [Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P68032)
20. [Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P68032)
21. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P68032)
22. [Protein profile of exosomes from trabecular meshwork cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P68032)
23. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P68032)
24. [Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P68032)
25. [Actin Mutations in Dilated Cardiomyopathy, a Heritable Form of Heart Failure](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P68032)
26. [Mutation in the alpha-cardiac actin gene associated with apical hypertrophic cardiomyopathy, left ventricular non-compaction, and septal defects](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P68032)
27. [α-cardiac actin mutations produce atrial septal defects](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P68032)
28. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P68032&geneProductId=UniProtKB:P68032)
29. Ensembl Release 99