Actin alpha 2, smooth muscle
type: Thing
description: mammalian protein found in Homo sapiens
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P352
  value: P62736
additional property: PropertyValue
  property ID: P361
  value: actin
additional property: PropertyValue
  property ID: P361
  value: Actin/actin-like conserved site, protein family
additional property: PropertyValue
  property ID: P361
  value: Actin, conserved site, protein family
additional property: PropertyValue
  property ID: P527
  value: Actin, conserved site
additional property: PropertyValue
  property ID: P527
  value: Actin/actin-like conserved site
additional property: PropertyValue
  property ID: P637
  value: NP_001135417
additional property: PropertyValue
  property ID: P637
  value: NP_001307784
additional property: PropertyValue
  property ID: P637
  value: NP_001604
additional property: PropertyValue
  property ID: P680
  value: ATP binding
additional property: PropertyValue
  property ID: P680
  value: nucleotide binding
additional property: PropertyValue
  property ID: P680
  value: protein kinase binding
additional property: PropertyValue
  property ID: P681
  value: cytosol
additional property: PropertyValue
  property ID: P681
  value: cytoplasm
additional property: PropertyValue
  property ID: P681
  value: actin cytoskeleton
additional property: PropertyValue
  property ID: P682
  value: muscle contraction
additional property: PropertyValue
  property ID: P682
  value: regulation of blood pressure
additional property: PropertyValue
  property ID: P682
  value: vascular associated smooth muscle contraction
additional property: PropertyValue
  property ID: P702
  value: ACTA2
additional property: PropertyValue
  property ID: P703
  value: Homo sapiens
additional property: PropertyValue
  property ID: P705
  value: ENSP00000224784
additional property: PropertyValue
  property ID: P705
  value: ENSP00000396730
additional property: PropertyValue
  property ID: P705
  value: ENSP00000398239
confidence:
  popularity graph score:
    score: 0.002
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 15
      unique citations norm: 0.006
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 15
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: P62736
    source count: 1
    confidence: 0.2
  P361:
    value: Q185269
    source count: 1
    confidence: 0.2
    value label: actin
  P361:
    value: Q95351236
    source count: 1
    confidence: 0.2
    value label: Actin/actin-like conserved site, protein family
  P361:
    value: Q95350788
    source count: 1
    confidence: 0.2
    value label: Actin, conserved site, protein family
  P527:
    value: Q24771571
    source count: 1
    confidence: 0.2
    value label: Actin, conserved site
  P527:
    value: Q24719556
    source count: 1
    confidence: 0.2
    value label: Actin/actin-like conserved site
  P637:
    value: NP_001135417
    source count: 1
    confidence: 0.2
  P637:
    value: NP_001307784
    source count: 1
    confidence: 0.2
  P637:
    value: NP_001604
    source count: 1
    confidence: 0.2
  P680:
    value: Q14817981
    source count: 1
    confidence: 0.2
    value label: ATP binding
  P680:
    value: Q14860365
    source count: 1
    confidence: 0.2
    value label: nucleotide binding
  P680:
    value: Q14817984
    source count: 2
    confidence: 0.4
    value label: protein kinase binding
  P681:
    value: Q220599
    source count: 1
    confidence: 0.2
    value label: cytosol
  P681:
    value: Q79899
    source count: 5
    confidence: 1.0
    value label: cytoplasm
  P681:
    value: Q14860845
    source count: 1
    confidence: 0.2
    value label: actin cytoskeleton
  P681:
    value: Q14878848
    source count: 1
    confidence: 0.2
    value label: smooth muscle contractile fiber
  P681:
    value: Q14864866
    source count: 1
    confidence: 0.2
    value label: cell body
  P682:
    value: Q127006
    source count: 1
    confidence: 0.2
    value label: muscle contraction
  P682:
    value: Q14819786
    source count: 1
    confidence: 0.2
    value label: regulation of blood pressure
  P682:
    value: Q21110400
    source count: 1
    confidence: 0.2
    value label: vascular associated smooth muscle contraction
  P682:
    value: Q21096419
    source count: 1
    confidence: 0.2
    value label: mesenchyme migration
  P682:
    value: Q14633893
    source count: 1
    confidence: 0.2
    value label: positive regulation of gene expression

value: Q17709258
source count: 1
confidence: 0.2
value label: ACTA2

value: Q15978631
source count: 1
confidence: 0.2
value label: Homo sapiens

value: ENSP00000224784
source count: 1
confidence: 0.2

value: ENSP00000396730
source count: 1
confidence: 0.2

value: ENSP00000398239
source count: 1
confidence: 0.2

source: GOA
stated in qid: Q28018111
retrieved: 2019-05-09

source: Development of glomerular endothelial cells, podocytes and mesangial cells in the human fetus and infant
stated in qid: Q24304110
retrieved: 2019-04-08

source: Cellular localization of cyclooxygenase-1 and cyclooxygenase-2 in the normal mouse, rat, and human retina
stated in qid: Q24307900
retrieved: 2019-04-08

source: Endothelial cell senescence in human atherosclerosis: role of telomere in endothelial dysfunction
stated in qid: Q24292963
retrieved: 2019-04-08

source: In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine
stated in qid: Q24337415
retrieved: 2017-09-26

source: Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy
stated in qid: Q24338381
retrieved: 2017-09-26

source: Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy
stated in qid: Q24338381
retrieved: 2019-05-09

source: Blood pressure is regulated by an alpha1D-adrenergic receptor/dystrophin signalosome
stated in qid: Q24311297
retrieved: 2019-05-09

source: In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine
stated in qid: Q24337415
retrieved: 2019-05-09

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2019-05-09

source: Transcriptomic and proteomic analyses of rhabdomyosarcoma cells reveal differential cellular gene expression in response to enterovirus 71 infection
stated in qid: Q24309119
retrieved: 2019-05-09

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2019-11-13

source: Q20641742
stated in qid: Q20641742
retrieved: 2020-05-30

source: Ensembl Release 99
stated in qid: Q83867711

wikidata id: Q21110401
domain: protein
level: standard
html url: https://4ort.xyz/entity/actin-alpha-2-smooth-muscle
markdown url: https://4ort.xyz/entity/actin-alpha-2-smooth-muscle.md
facts url summary: https://4ort.xyz/entity/actin-alpha-2-smooth-muscle/facts.json
facts url standard: https://4ort.xyz/entity/actin-alpha-2-smooth-muscle/facts.json
facts url full: https://4ort.xyz/entity/actin-alpha-2-smooth-muscle/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-24T16:40:51.388512Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T13:58:50.900290+00:00Z