Aconitase 1
type: Thing
description: mammalian protein found in Mus musculus
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P279
  value: protein
additional property: PropertyValue
  property ID: P352
  value: P28271
additional property: PropertyValue
  property ID: P361
  value: Aconitase/3-isopropylmalate dehydratase, swivel
additional property: PropertyValue
  property ID: P361
  value: Aconitase, iron-sulfur domain
additional property: PropertyValue
  property ID: P361
  value: Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3
additional property: PropertyValue
  property ID: P527
  value: Aconitase A/isopropylmalate dehydratase small subunit, swivel domain
additional property: PropertyValue
  property ID: P527
  value: Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain
additional property: PropertyValue
  property ID: P527
  value: Aconitase family, 4Fe-4S cluster binding site
additional property: PropertyValue
  property ID: P637
  value: NP_031412
additional property: PropertyValue
  property ID: P637
  value: XP_036019494
additional property: PropertyValue
  property ID: P680
  value: 4 iron, 4 sulfur cluster binding
additional property: PropertyValue
  property ID: P680
  value: aconitate hydratase activity
additional property: PropertyValue
  property ID: P680
  value: metal ion binding
additional property: PropertyValue
  property ID: P681
  value: cytosol
additional property: PropertyValue
  property ID: P681
  value: Golgi apparatus
additional property: PropertyValue
  property ID: P681
  value: endoplasmic reticulum
additional property: PropertyValue
  property ID: P682
  value: response to iron(II) ion
additional property: PropertyValue
  property ID: P682
  value: citrate metabolic process
additional property: PropertyValue
  property ID: P682
  value: tricarboxylic acid cycle
additional property: PropertyValue
  property ID: P702
  value: Aco1
additional property: PropertyValue
  property ID: P703
  value: house mouse
additional property: PropertyValue
  property ID: P705
  value: ENSMUSP00000100038
confidence:
  popularity graph score:
    score: 0.002
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 18
      unique citations norm: 0.007
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 18
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P279:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: P28271
    source count: 1
    confidence: 0.2
  P361:
    value: Q24776984
    source count: 1
    confidence: 0.2
    value label: Aconitase/3-isopropylmalate dehydratase, swivel
  P361:
    value: Q41797152
    source count: 1
    confidence: 0.2
    value label: Aconitase, iron-sulfur domain
  P361:
    value: Q24725477
    source count: 1
    confidence: 0.2
    value label: Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3
  P361:
    value: Q24780747
    source count: 1
    confidence: 0.2
    value label: iron regulatory protein 1
  P361:
    value: Q83145957
    source count: 1
    confidence: 0.2
    value label: Aconitase A/isopropylmalate dehydratase small subunit, swivel domain, protein family
  P527:
    value: Q24772471
    source count: 1
    confidence: 0.2
    value label: Aconitase A/isopropylmalate dehydratase small subunit, swivel domain
  P527:
    value: Q24723456
    source count: 1
    confidence: 0.2
    value label: Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain
  P527:
    value: Q24726866
    source count: 1
    confidence: 0.2
    value label: Aconitase family, 4Fe-4S cluster binding site
  P637:
    value: NP_031412
    source count: 1
    confidence: 0.2
  P637:
    value: XP_036019494
    source count: 1
    confidence: 0.2
  P680:
    value: Q14883421
    source count: 5
    confidence: 1.0
    value label: 4 iron, 4 sulfur cluster binding
  P680:
    value: Q21096282
    source count: 7
    confidence: 1.0
    value label: aconitate hydratase activity
  P680:
    value: Q13667380
    source count: 1
    confidence: 0.2
    value label: metal ion binding
  P680:
    value: Q14904850
    source count: 7
    confidence: 1.0
    value label: iron-responsive element binding
  P680:
    value: Q14859873
    source count: 1
    confidence: 0.2
    value label: lyase activity
  P681:
    value: Q220599
    source count: 4
    confidence: 0.8
    value label: cytosol
  P681:
    value: Q83181
    source count: 2
    confidence: 0.4
    value label: Golgi apparatus
  P681:
    value: Q79927
    source count: 2
    confidence: 0.4
    value label: endoplasmic reticulum
  P681:
    value: Q39572
    source count: 3
    confidence: 0.6
    value label: mitochondrion
  P681:
    value: Q79899
    source count: 4
    confidence: 0.8
    value label: cytoplasm

value: Q14860872
source count: 4
confidence: 0.8
value label: response to iron(II) ion

value: Q14907617
source count: 3
confidence: 0.6
value label: citrate metabolic process

value: Q133895
source count: 1
confidence: 0.2
value label: tricarboxylic acid cycle

value: Q4374357
source count: 1
confidence: 0.2
value label: post-embryonic development

value: Q411391
source count: 1
confidence: 0.2
value label: regulation of gene expression

value: Q18218496
source count: 1
confidence: 0.2
value label: Aco1

value: Q83310
source count: 1
confidence: 0.2
value label: house mouse

value: ENSMUSP00000100038
source count: 1
confidence: 0.2

source: GOA
stated in qid: Q28018111
retrieved: 2018-01-31

source: Genetic ablations of iron regulatory proteins 1 and 2 reveal why iron regulatory protein 2 dominates iron homeostasis
stated in qid: Q28505771
retrieved: 2018-01-31

source: Mammalian tissue oxygen levels modulate iron-regulatory protein activities in vivo
stated in qid: Q28591638
retrieved: 2018-01-31

source: GOA
stated in qid: Q28018111
retrieved: 2019-04-08

source: Genetic ablations of iron regulatory proteins 1 and 2 reveal why iron regulatory protein 2 dominates iron homeostasis
stated in qid: Q28505771
retrieved: 2019-02-14

source: Mammalian tissue oxygen levels modulate iron-regulatory protein activities in vivo
stated in qid: Q28591638
retrieved: 2019-02-14

source: Characterization of a second RNA-binding protein in rodents with specificity for iron-responsive elements
stated in qid: Q28257448
retrieved: 2019-02-14

source: Induction of iron regulatory protein 1 RNA-binding activity by nitric oxide is associated with a concomitant increase in the labile iron pool: implications for DNA damage
stated in qid: Q28513474
retrieved: 2019-02-14

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2019-04-08

source: Subcellular localization of iron regulatory proteins to Golgi and ER membranes
stated in qid: Q24320755
retrieved: 2018-01-31

source: A mitochondrial protein compendium elucidates complex I disease biology
stated in qid: Q24655079
retrieved: 2018-01-31

source: A mitochondrial protein compendium elucidates complex I disease biology
stated in qid: Q24655079
retrieved: 2019-04-08

source: Subcellular localization of iron regulatory proteins to Golgi and ER membranes
stated in qid: Q24320755
retrieved: 2019-04-08

source: Iron regulatory proteins are essential for intestinal function and control key iron absorption molecules in the duodenum
stated in qid: Q28591722
retrieved: 2019-04-08

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2022-05-25

source: Q20641742
stated in qid: Q20641742
retrieved: 2022-03-20

source: ensembl Release 106
stated in qid: Q111699881

wikidata id: Q21499437
domain: protein
level: standard
html url: https://4ort.xyz/entity/aconitase-1
markdown url: https://4ort.xyz/entity/aconitase-1.md
facts url summary: https://4ort.xyz/entity/aconitase-1/facts.json
facts url standard: https://4ort.xyz/entity/aconitase-1/facts.json
facts url full: https://4ort.xyz/entity/aconitase-1/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-24T21:37:51.711036Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T13:58:50.900290+00:00Z