# Aconitase 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21096283](https://www.wikidata.org/wiki/Q21096283)  
**Source**: https://4ort.xyz/entity/aconitase-1-q21096283


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P21399)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21399)
5. [Control of iron homeostasis by an iron-regulated ubiquitin ligase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21399)
6. [An E3 ligase possessing an iron-responsive hemerythrin domain is a regulator of iron homeostasis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21399)
7. [A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21399)
8. [Homology between IRE-BP, a regulatory RNA-binding protein, aconitase, and isopropylmalate isomerase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21399)
9. [A regulated RNA binding protein also possesses aconitase activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21399)
10. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P21399&geneProductId=UniProtKB:P21399)
11. [Cellular regulation of the iron-responsive element binding protein: disassembly of the cubane iron-sulfur cluster results in high-affinity RNA binding](http://www.ebi.ac.uk/QuickGO/annotations?protein=P21399&geneProductId=UniProtKB:P21399)
12. [The bifunctional iron-responsive element binding protein/cytosolic aconitase: the role of active-site residues in ligand binding and regulation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P21399&geneProductId=UniProtKB:P21399)
13. [A regulated RNA binding protein also possesses aconitase activity](http://www.ebi.ac.uk/QuickGO/annotations?protein=P21399&geneProductId=UniProtKB:P21399)
14. [Human CIA2A-FAM96A and CIA2B-FAM96B integrate iron homeostasis and maturation of different subsets of cytosolic-nuclear iron-sulfur proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21399)
15. [Cellular regulation of the iron-responsive element binding protein: disassembly of the cubane iron-sulfur cluster results in high-affinity RNA binding](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21399)
16. [The bifunctional iron-responsive element binding protein/cytosolic aconitase: the role of active-site residues in ligand binding and regulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21399)
17. [Crystal structure of human iron regulatory protein 1 as cytosolic aconitase](http://www.ebi.ac.uk/QuickGO/annotations?protein=P21399&geneProductId=UniProtKB:P21399)
18. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P21399&geneProductId=UniProtKB:P21399)
19. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21399)
20. [Crystal structure of human iron regulatory protein 1 as cytosolic aconitase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21399)
21. [Subcellular localization of iron regulatory proteins to Golgi and ER membranes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21399)
22. [Proteomic analysis of podocyte exosome-enriched fraction from normal human urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P21399&geneProductId=UniProtKB:P21399)
23. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P21399&geneProductId=UniProtKB:P21399)
24. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P21399&geneProductId=UniProtKB:P21399)
25. [Expression of active iron regulatory factor from a full length human cDNA byin vitrotranscription/translation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21399)
26. [Roles of the mammalian cytosolic cysteine desulfurase, ISCS, and scaffold protein, ISCU, in iron-sulfur cluster assembly](http://www.ebi.ac.uk/QuickGO/annotations?protein=P21399&geneProductId=UniProtKB:P21399)
27. [Roles of the mammalian cytosolic cysteine desulfurase, ISCS, and scaffold protein, ISCU, in iron-sulfur cluster assembly](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21399)
28. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21399)
29. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21399)
30. Ensembl Release 99
31. UMLS 2023