# acetylcholinesterase

> mammalian protein found in Homo sapiens

**Wikidata**: [Q22676679](https://www.wikidata.org/wiki/Q22676679)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/Acetylcholinesterase)  
**Source**: https://4ort.xyz/entity/acetylcholinesterase


## References

1. UniProt
2. IUPHAR/BPS Guide to PHARMACOLOGY
3. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL812)
4. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL1128)
5. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL1201341)
6. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL748)
7. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL1200541)
8. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL1678)
9. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P22303)
10. Q20641742
11. [Mutagenesis of human acetylcholinesterase. Identification of residues involved in catalytic activity and in polypeptide folding](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22303)
12. [Human acetylcholinesterase binds to mouse laminin-1 and human collagen IV by an electrostatic mechanism at the peripheral anionic site](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22303)
13. [Dissection of the human acetylcholinesterase active center determinants of substrate specificity. Identification of residues constituting the anionic site, the hydrophobic site, and the acyl pocket](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22303)
14. [Fractional diffusion-limited component of reactions catalyzed by acetylcholinesterase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22303)
15. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P22303&geneProductId=UniProtKB:P22303)
16. [Acetylcholinesterase--new roles for an old actor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22303)
17. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22303)
18. [Hydrophobic protein that copurifies with human brain acetylcholinesterase: amino acid sequence, genomic organization, and chromosomal localization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22303)
19. [The synaptic acetylcholinesterase tetramer assembles around a polyproline II helix](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22303)
20. [Acetylcholinesterase-R increases germ cell apoptosis but enhances sperm motility](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22303)
21. [Mutagenesis of human acetylcholinesterase. Identification of residues involved in catalytic activity and in polypeptide folding](http://www.ebi.ac.uk/QuickGO/annotations?protein=P22303&geneProductId=UniProtKB:P22303)
22. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22303)
23. [Characterization of acetylcholinesterase expression and secretion during osteoblast differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22303)
24. [Biochemical characterization of human umbilical vein endothelial cell membrane bound acetylcholinesterase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22303)
25. [Expression of a human acetylcholinesterase promoter-reporter construct in developing neuromuscular junctions of Xenopus embryos](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22303)
26. [Activation/deactivation of acetylcholinesterase by H2O2: more evidence for oxidative stress in vitiligo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22303)
27. [Acetylcholinesterase and molecular interactions at the neuromuscular junction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22303)
28. [Role of acetylcholinesterase inhibitors in the metabolism of amyloid precursor protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22303)
29. [Reduced nicotinic receptor function in sympathetic ganglia is responsible for the hypothermia in the acetylcholinesterase knockout mouse](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22303)
30. Ensembl Release 99
31. [OpenAlex](https://docs.openalex.org/download-snapshot/snapshot-data-format)