A-Raf proto-oncogene, serine/threonine kinase
type: Thing
description: mammalian protein found in Rattus norvegicus
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P279
  value: protein
additional property: PropertyValue
  property ID: P352
  value: P14056
additional property: PropertyValue
  property ID: P361
  value: Ubiquitin-like domain superfamily
additional property: PropertyValue
  property ID: P361
  value: Protein kinase-like domain superfamily
additional property: PropertyValue
  property ID: P361
  value: Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family
additional property: PropertyValue
  property ID: P527
  value: serine/threonine-protein kinase, active site
additional property: PropertyValue
  property ID: P527
  value: protein kinase, ATP binding site
additional property: PropertyValue
  property ID: P527
  value: serine-threonine/tyrosine-protein kinase, catalytic domain
additional property: PropertyValue
  property ID: P637
  value: NP_001028835
additional property: PropertyValue
  property ID: P637
  value: NP_071977
additional property: PropertyValue
  property ID: P637
  value: XP_038955949
additional property: PropertyValue
  property ID: P680
  value: nucleotide binding
additional property: PropertyValue
  property ID: P680
  value: protein kinase activity
additional property: PropertyValue
  property ID: P680
  value: protein serine/threonine kinase activity
additional property: PropertyValue
  property ID: P681
  value: mitochondrion
additional property: PropertyValue
  property ID: P681
  value: cytosol
additional property: PropertyValue
  property ID: P682
  value: MAPK cascade
additional property: PropertyValue
  property ID: P682
  value: protein phosphorylation
additional property: PropertyValue
  property ID: P682
  value: signal transduction
additional property: PropertyValue
  property ID: P702
  value: Araf
additional property: PropertyValue
  property ID: P703
  value: brown rat
additional property: PropertyValue
  property ID: P705
  value: ENSRNOP00000048890
additional property: PropertyValue
  property ID: P705
  value: ENSRNOP00000082142
confidence:
  popularity graph score:
    score: 0.001
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 8
      unique citations norm: 0.003
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 8
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P279:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: P14056
    source count: 1
    confidence: 0.2
  P361:
    value: Q24725964
    source count: 1
    confidence: 0.2
    value label: Ubiquitin-like domain superfamily
  P361:
    value: Q24726164
    source count: 1
    confidence: 0.2
    value label: Protein kinase-like domain superfamily
  P361:
    value: Q83137014
    source count: 1
    confidence: 0.2
    value label: Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family
  P361:
    value: Q83134938
    source count: 1
    confidence: 0.2
    value label: Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, protein family
  P361:
    value: Q83132853
    source count: 1
    confidence: 0.2
    value label: Diacylglycerol/phorbol-ester binding domain, protein family
  P527:
    value: Q24787419
    source count: 1
    confidence: 0.2
    value label: serine/threonine-protein kinase, active site
  P527:
    value: Q24769051
    source count: 1
    confidence: 0.2
    value label: protein kinase, ATP binding site
  P527:
    value: Q24740842
    source count: 1
    confidence: 0.2
    value label: serine-threonine/tyrosine-protein kinase, catalytic domain
  P527:
    value: Q24721120
    source count: 1
    confidence: 0.2
    value label: diacylglycerol/phorbol-ester binding
  P527:
    value: Q24768234
    source count: 1
    confidence: 0.2
    value label: protein kinase domain
  P637:
    value: NP_001028835
    source count: 1
    confidence: 0.2
  P637:
    value: NP_071977
    source count: 1
    confidence: 0.2
  P637:
    value: XP_038955949
    source count: 1
    confidence: 0.2
  P680:
    value: Q14860365
    source count: 1
    confidence: 0.2
    value label: nucleotide binding
  P680:
    value: Q14820641
    source count: 1
    confidence: 0.2
    value label: protein kinase activity
  P680:
    value: Q14326094
    source count: 2
    confidence: 0.4
    value label: protein serine/threonine kinase activity
  P680:
    value: Q14865542
    source count: 2
    confidence: 0.4
    value label: MAP kinase kinase kinase activity
  P680:
    value: Q14817981
    source count: 2
    confidence: 0.4
    value label: ATP binding
  P681:
    value: Q39572
    source count: 2
    confidence: 0.4
    value label: mitochondrion
  P681:
    value: Q220599
    source count: 3
    confidence: 0.6
    value label: cytosol

value: Q14758900
source count: 1
confidence: 0.2
value label: MAPK cascade

value: Q7251493
source count: 3
confidence: 0.6
value label: protein phosphorylation

value: Q828130
source count: 1
confidence: 0.2
value label: signal transduction

value: Q242736
source count: 1
confidence: 0.2
value label: phosphorylation

value: Q21101379
source count: 1
confidence: 0.2
value label: regulation of TOR signaling

value: Q24422761
source count: 1
confidence: 0.2
value label: Araf

value: Q184224
source count: 1
confidence: 0.2
value label: brown rat

value: ENSRNOP00000048890
source count: 1
confidence: 0.2

value: ENSRNOP00000082142
source count: 1
confidence: 0.2

source: GOA
stated in qid: Q28018111
retrieved: 2019-02-14

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2019-02-14

source: Expression of mitogen-activated protein kinase pathways during postnatal development of rat heart
stated in qid: Q28581967
retrieved: 2019-02-14

source: Hepatic epidermal growth factor-regulated mitogen-activated protein kinase kinase kinase activity in the rat: lack of identity with known forms of raf and MEKK
stated in qid: Q28584105
retrieved: 2019-02-14

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2022-05-25

source: Q20641742
stated in qid: Q20641742
retrieved: 2022-03-20

source: ensembl Release 106
stated in qid: Q111699881

wikidata id: Q28563222
domain: protein
level: standard
html url: https://4ort.xyz/entity/a-raf-proto-oncogene-serine-threonine-kinase-q28563222
markdown url: https://4ort.xyz/entity/a-raf-proto-oncogene-serine-threonine-kinase-q28563222.md
facts url summary: https://4ort.xyz/entity/a-raf-proto-oncogene-serine-threonine-kinase-q28563222/facts.json
facts url standard: https://4ort.xyz/entity/a-raf-proto-oncogene-serine-threonine-kinase-q28563222/facts.json
facts url full: https://4ort.xyz/entity/a-raf-proto-oncogene-serine-threonine-kinase-q28563222/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-06T00:56:15.048925Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T14:26:41.845951+00:00Z