5-methyltetrahydrofolate-homocysteine methyltransferase
type: Thing
description: mammalian protein found in Mus musculus
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P279
  value: protein
additional property: PropertyValue
  property ID: P352
  value: A6H5Y3
additional property: PropertyValue
  property ID: P361
  value: Cobalamin-binding domain superfamily
additional property: PropertyValue
  property ID: P361
  value: Cobalamin-dependent methionine synthase
additional property: PropertyValue
  property ID: P361
  value: Dihydropteroate synthase-like
additional property: PropertyValue
  property ID: P527
  value: Methionine synthase, B12-binding domain
additional property: PropertyValue
  property ID: P527
  value: Cobalamin (vitamin B12)-binding module, cap domain
additional property: PropertyValue
  property ID: P527
  value: Pterin-binding domain
additional property: PropertyValue
  property ID: P637
  value: NP_001074597
additional property: PropertyValue
  property ID: P637
  value: XP_006516724
additional property: PropertyValue
  property ID: P680
  value: transferase activity
additional property: PropertyValue
  property ID: P680
  value: methionine synthase activity
additional property: PropertyValue
  property ID: P680
  value: cobalamin binding
additional property: PropertyValue
  property ID: P681
  value: cytoplasm
additional property: PropertyValue
  property ID: P681
  value: cytosol
additional property: PropertyValue
  property ID: P682
  value: cobalamin metabolic process
additional property: PropertyValue
  property ID: P682
  value: cellular amino acid biosynthetic process
additional property: PropertyValue
  property ID: P682
  value: methionine biosynthetic process
additional property: PropertyValue
  property ID: P702
  value: Mtr
additional property: PropertyValue
  property ID: P703
  value: house mouse
additional property: PropertyValue
  property ID: P705
  value: ENSMUSP00000097442
additional property: PropertyValue
  property ID: P705
  value: ENSMUSP00000152579
confidence:
  popularity graph score:
    score: 0.001
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 9
      unique citations norm: 0.004
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 9
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P279:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: A6H5Y3
    source count: 1
    confidence: 0.2
  P361:
    value: Q41797824
    source count: 1
    confidence: 0.2
    value label: Cobalamin-binding domain superfamily
  P361:
    value: Q24779264
    source count: 1
    confidence: 0.2
    value label: Cobalamin-dependent methionine synthase
  P361:
    value: Q24780168
    source count: 1
    confidence: 0.2
    value label: Dihydropteroate synthase-like
  P361:
    value: Q41797691
    source count: 1
    confidence: 0.2
    value label: Homocysteine-binding domain superfamily
  P361:
    value: Q41798101
    source count: 1
    confidence: 0.2
    value label: Vitamin B12-dependent methionine synthase, activation domain superfamily
  P527:
    value: Q24786110
    source count: 1
    confidence: 0.2
    value label: Methionine synthase, B12-binding domain
  P527:
    value: Q24773126
    source count: 1
    confidence: 0.2
    value label: Cobalamin (vitamin B12)-binding module, cap domain
  P527:
    value: Q24786498
    source count: 1
    confidence: 0.2
    value label: Pterin-binding domain
  P527:
    value: Q24787550
    source count: 1
    confidence: 0.2
    value label: Cobalamin (vitamin B12)-binding domain
  P527:
    value: Q24726886
    source count: 1
    confidence: 0.2
    value label: Homocysteine-binding domain
  P637:
    value: NP_001074597
    source count: 1
    confidence: 0.2
  P637:
    value: XP_006516724
    source count: 1
    confidence: 0.2
  P680:
    value: Q14840131
    source count: 1
    confidence: 0.2
    value label: transferase activity
  P680:
    value: Q14876908
    source count: 5
    confidence: 1.0
    value label: methionine synthase activity
  P680:
    value: Q14859650
    source count: 2
    confidence: 0.4
    value label: cobalamin binding
  P680:
    value: Q14633865
    source count: 1
    confidence: 0.2
    value label: zinc ion binding
  P680:
    value: Q13667380
    source count: 2
    confidence: 0.4
    value label: metal ion binding
  P681:
    value: Q79899
    source count: 1
    confidence: 0.2
    value label: cytoplasm
  P681:
    value: Q220599
    source count: 3
    confidence: 0.6
    value label: cytosol
  P682:
    value: Q14859652
    source count: 2
    confidence: 0.4
    value label: cobalamin metabolic process

value: Q14851773
source count: 1
confidence: 0.2
value label: cellular amino acid biosynthetic process

value: Q14864918
source count: 5
confidence: 1.0
value label: methionine biosynthetic process

value: Q518328
source count: 1
confidence: 0.2
value label: methylation

value: Q13416689
source count: 1
confidence: 0.2
value label: cell metabolism

value: Q14876917
source count: 1
confidence: 0.2
value label: Mtr

value: Q83310
source count: 1
confidence: 0.2
value label: house mouse

value: ENSMUSP00000097442
source count: 1
confidence: 0.2

value: ENSMUSP00000152579
source count: 1
confidence: 0.2

source: GOA
stated in qid: Q28018111
retrieved: 2019-02-14

source: GOA
stated in qid: Q28018111
retrieved: 2018-04-24

source: Targeted disruption of the methionine synthase gene in mice
stated in qid: Q28594791
retrieved: 2018-04-24

source: Targeted disruption of the methionine synthase gene in mice
stated in qid: Q28594791
retrieved: 2019-02-14

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2019-02-14

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2022-05-25

source: Q20641742
stated in qid: Q20641742
retrieved: 2022-03-20

source: ensembl Release 106
stated in qid: Q111699881

wikidata id: Q14876926
domain: protein
level: standard
html url: https://4ort.xyz/entity/5-methyltetrahydrofolate-homocysteine-methyltransferase-q14876926
markdown url: https://4ort.xyz/entity/5-methyltetrahydrofolate-homocysteine-methyltransferase-q14876926.md
facts url summary: https://4ort.xyz/entity/5-methyltetrahydrofolate-homocysteine-methyltransferase-q14876926/facts.json
facts url standard: https://4ort.xyz/entity/5-methyltetrahydrofolate-homocysteine-methyltransferase-q14876926/facts.json
facts url full: https://4ort.xyz/entity/5-methyltetrahydrofolate-homocysteine-methyltransferase-q14876926/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-04T16:38:33.049168Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T14:10:53.568599+00:00Z