# 5-hydroxytryptamine receptor 2C

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28557794](https://www.wikidata.org/wiki/Q28557794)  
**Source**: https://4ort.xyz/entity/5-hydroxytryptamine-receptor-2c


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P08909)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08909)
5. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08909)
6. [Mutagenesis analysis of the serotonin 5-HT2C receptor and a Caenorhabditis elegans 5-HT2 homologue: conserved residues of helix 4 and helix 7 contribute to agonist-dependent activation of 5-HT2 receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08909)
7. [Reconstitution of B cell antigen receptor-induced signaling events in a nonlymphoid cell line by expressing the Syk protein-tyrosine kinase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08909)
8. [Disruption of PTEN coupling with 5-HT2C receptors suppresses behavioral responses induced by drugs of abuse](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08909)
9. [The membrane IgM-associated proteins MB-1 and Ig-beta are sufficient to promote surface expression of a partially functional B-cell antigen receptor in a nonlymphoid cell line](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08909)
10. [Regulation of serotonin-2C receptor G-protein coupling by RNA editing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08909)
11. [Phospholipase D activation by endogenous 5-hydroxytryptamine 2C receptors is mediated by Galpha13 and pertussis toxin-insensitive Gbetagamma subunits](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08909)
12. [WAY-163909 [(7bR, 10aR)-1,2,3,4,8,9,10,10a-octahydro-7bH-cyclopenta-[b][1,4]diazepino[6,7,1hi]indole], a novel 5-hydroxytryptamine 2C receptor-selective agonist with anorectic activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08909)
13. [In vivo evidence that 5-HT(2C) receptors inhibit 5-HT neuronal activity via a GABAergic mechanism](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08909)
14. [Activation of 5-HT2 receptors enhances the release of acetylcholine in the prefrontal cortex and hippocampus of the rat](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08909)
15. [Increased 5-HT2C receptor binding in the brain stem and cerebral cortex during liver regeneration and hepatic neoplasia in rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08909)
16. [The serotonin 2C receptor agonist Ro-60-0175 attenuates effects of nicotine in the five-choice serial reaction time task and in drug discrimination](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08909)
17. [Differential effects of 5-HT2C receptor ligands on place conditioning and locomotor activity in rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08909)
18. [Vasoconstrictor responses to 5-hydroxytryptamine in the autoperfused hindquarters of spontaneously hypertensive rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08909)
19. [Region-dependent regulation of mesoaccumbens dopamine neurons in vivo by the constitutive activity of central serotonin2C receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08909)
20. [Possible involvement of spinal noradrenergic mechanisms in the antiallodynic effect of intrathecally administered 5-HT2C receptor agonists in the rats with peripheral nerve injury](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08909)
21. ensembl Release 106