# 5'-3' exoribonuclease 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21245962](https://www.wikidata.org/wiki/Q21245962)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/XRN1_(gene))  
**Source**: https://4ort.xyz/entity/5-3-exoribonuclease-1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q8IZH2)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZH2)
5. [Exonuclease hDIS3L2 specifies an exosome‐independent 3′‐5′ degradation pathway of human cytoplasmic mRNA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZH2)
6. [Recruitment and activation of mRNA decay enzymes by two ARE-mediated decay activation domains in the proteins TTP and BRF-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZH2)
7. [Regulation of m6A Transcripts by the 3'→5' RNA Helicase YTHDC2 Is Essential for a Successful Meiotic Program in the Mammalian Germline.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZH2)
8. [Zinc-finger antiviral protein inhibits HIV-1 infection by selectively targeting multiply spliced viral mRNAs for degradation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZH2)
9. [The mammalian TRIM-NHL protein TRIM71/LIN-41 is a repressor of mRNA function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZH2)
10. [Human Pat1b Connects Deadenylation with mRNA Decapping and Controls the Assembly of Processing Bodies](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZH2)
11. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IZH2&geneProductId=UniProtKB:Q8IZH2)
12. [The mRNA-Bound Proteome and Its Global Occupancy Profile on Protein-Coding Transcripts](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IZH2&geneProductId=UniProtKB:Q8IZH2)
13. [Insights into RNA Biology from an Atlas of Mammalian mRNA-Binding Proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IZH2&geneProductId=UniProtKB:Q8IZH2)
14. [Inhibition of telomerase RNA decay rescues telomerase deficiency caused by dyskerin or PARN defects](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZH2)
15. [The mRNA-Bound Proteome and Its Global Occupancy Profile on Protein-Coding Transcripts](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZH2)
16. [Insights into RNA Biology from an Atlas of Mammalian mRNA-Binding Proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZH2)
17. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IZH2&geneProductId=UniProtKB:Q8IZH2)
18. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZH2)
19. [Addition of poly(A) and poly(A)-rich tails during RNA degradation in the cytoplasm of human cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZH2)
20. [Human cell growth requires a functional cytoplasmic exosome, which is involved in various mRNA decay pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZH2)
21. [Degradation of histone mRNA requires oligouridylation followed by decapping and simultaneous degradation of the mRNA both 5′ to 3′ and 3′ to 5′](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZH2)
22. Ensembl Release 99