# 3-hydroxy-3-methylglutaryl-CoA synthase 1

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28558167](https://www.wikidata.org/wiki/Q28558167)  
**Source**: https://4ort.xyz/entity/3-hydroxy-3-methylglutaryl-coa-synthase-1-q28558167


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P17425)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17425)
5. [Nucleotide sequence of a rat liver cDNA encoding the cytosolic 3-hydroxy-3-methylglutaryl coenzyme A synthase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17425)
6. [Binding site for fungal beta-lactone hymeglusin on cytosolic 3-hydroxy-3-methylglutaryl coenzyme A synthase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17425)
7. [Inhibition of 3-hydroxy-3-methylglutaryl-CoA synthase and cholesterol biosynthesis by beta-lactone inhibitors and binding of these inhibitors to the enzyme](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17425)
8. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17425)
9. [Inactivation of thiolase by 2-alkynoyl-CoA via its intrinsic isomerase activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17425)
10. [The course of ketosis and the activity of key enzymes of ketogenesis and ketone-body utilization during development of the postnatal rat](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17425)
11. [Cytosolic 3-hydroxy-3-methyl glutaryl coenzyme a synthase in rat brain: Properties and developmental change](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17425)
12. [Tissue-specific transcriptional regulation of the cholesterol biosynthetic pathway leads to accumulation of testis meiosis-activating sterol (T-MAS)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17425)
13. [Diurnal rhythm of rat liver cytosolic 3-hydroxy-3-methylglutaryl-CoA synthase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17425)
14. [Regulation of cytosolic 3-hydroxy-3-methylglutaryl-CoA synthase mRNA levels by L-tri-iodothyronine](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17425)
15. [Molecular cloning and sequence of a cholesterol-repressible enzyme related to prenyltransferase in the isoprene biosynthetic pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17425)
16. [Actein activates stress- and statin-associated responses and is bioavailable in Sprague-Dawley rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17425)
17. [Regulation of cholesterol synthesis in rat adrenal gland through coordinate control of 3-hydroxy-3-methylglutaryl coenzyme A synthase and reductase activities](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17425)
18. [Alpha-tocopherol affects androgen metabolism in male rat](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17425)
19. [Regulation of luteinizing hormone/chorionic gonadotropin receptor messenger ribonucleic acid expression in the rat ovary: relationship to cholesterol metabolism](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17425)
20. [Formation of intranuclear crystalloids and proliferation of the smooth endoplasmic reticulum in schwann cells induced by tellurium treatment: association with overexpression of HMG CoA reductase and HMG CoA synthase mRNA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17425)
21. [Lipogenic potential in liver of the preweanling rat: influence of dietary cholesterol](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17425)
22. [FSH and FOXO1 regulate genes in the sterol/steroid and lipid biosynthetic pathways in granulosa cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17425)
23. [The effect of 24S-hydroxycholesterol on cholesterol homeostasis in neurons: quantitative changes to the cortical neuron proteome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17425)
24. [Cafestol, the Cholesterol-Raising Factor in Boiled Coffee, Suppresses Bile Acid Synthesis by Downregulation of Cholesterol 7α-Hydroxylase and Sterol 27-Hydroxylase in Rat Hepatocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17425)
25. ensembl Release 104