# 3-hydroxy-3-methylglutaryl-CoA reductase

> mammalian protein found in Homo sapiens

**Wikidata**: [Q415607](https://www.wikidata.org/wiki/Q415607)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/HMG-CoA_reductase)  
**Source**: https://4ort.xyz/entity/3-hydroxy-3-methylglutaryl-coa-reductase


## References

1. UniProt
2. IUPHAR/BPS Guide to PHARMACOLOGY
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P04035)
4. Q20641742
5. Freebase Data Dumps. 2013
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04035)
7. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04035)
8. [The UBIAD1 prenyltransferase links menaquinone-4 [corrected] synthesis to cholesterol metabolic enzymes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04035)
9. [Crystal structure of the catalytic portion of human HMG-CoA reductase: insights into regulation of activity and catalysis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04035)
10. [Human 3-hydroxy-3-methylglutaryl coenzyme A reductase. Conserved domains responsible for catalytic activity and sterol-regulated degradation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P04035&geneProductId=UniProtKB:P04035)
11. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P04035&geneProductId=UniProtKB:P04035)
12. [Localization of the pre-squalene segment of the isoprenoid biosynthetic pathway in mammalian peroxisomes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P04035&geneProductId=UniProtKB:P04035)
13. [Localization of the pre-squalene segment of the isoprenoid biosynthetic pathway in mammalian peroxisomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04035)
14. [Human 3-hydroxy-3-methylglutaryl coenzyme A reductase. Conserved domains responsible for catalytic activity and sterol-regulated degradation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04035)
15. [Artemisinic acid inhibits melanogenesis through downregulation of C/EBP α-dependent expression of HMG-CoA reductase gene](http://www.ebi.ac.uk/QuickGO/annotations?protein=P04035&geneProductId=UniProtKB:P04035)
16. [Artemisinic acid inhibits melanogenesis through downregulation of C/EBP α-dependent expression of HMG-CoA reductase gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04035)
17. Ensembl Release 99
18. Identifiers.org
19. Transporter Classification database
20. [OpenAlex](https://docs.openalex.org/download-snapshot/snapshot-data-format)