# 2'-5'-oligoadenylate synthetase 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21096374](https://www.wikidata.org/wiki/Q21096374)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/OAS1)  
**Source**: https://4ort.xyz/entity/2-5-oligoadenylate-synthetase-1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P00973)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00973)
5. [A Proteome-Scale Map of the Human Interactome Network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00973)
6. [A Y2H-seq approach defines the human protein methyltransferase interactome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00973)
7. [Hepatitis C virus NS5A protein interacts with 2′,5′-oligoadenylate synthetase and inhibits antiviral activity of IFN in an IFN sensitivity-determining region-independent manner](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00973)
8. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P00973&geneProductId=UniProtKB:P00973)
9. [Characterization of the 2'-5'-oligoadenylate synthetase ubiquitin-like family](http://www.ebi.ac.uk/QuickGO/annotations?protein=P00973&geneProductId=UniProtKB:P00973)
10. [Structural basis for cytosolic double-stranded RNA surveillance by human oligoadenylate synthetase 1](http://www.ebi.ac.uk/QuickGO/annotations?protein=P00973&geneProductId=UniProtKB:P00973)
11. [The Oligoadenylate Synthetase Family: An Ancient Protein Family with Multiple Antiviral Activities](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00973)
12. [Full‐length sequence and expression of the 42 kDa 2–5A synthetase induced by human interferon](http://www.ebi.ac.uk/QuickGO/annotations?protein=P00973&geneProductId=UniProtKB:P00973)
13. [Structure and Expression of a Cloned cDNA for Human (2′-5′)Oligoadenylate Synthetase1](http://www.ebi.ac.uk/QuickGO/annotations?protein=P00973&geneProductId=UniProtKB:P00973)
14. [Inhibition of 2′‐5′ oligoadenylate synthetase by divalent metal ions](http://www.ebi.ac.uk/QuickGO/annotations?protein=P00973&geneProductId=UniProtKB:P00973)
15. [Characterization of the 2'-5'-oligoadenylate synthetase ubiquitin-like family](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00973)
16. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00973)
17. [Structural basis for cytosolic double-stranded RNA surveillance by human oligoadenylate synthetase 1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00973)
18. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P00973&geneProductId=UniProtKB:P00973)
19. [Human 2′-phosphodiesterase localizes to the mitochondrial matrix with a putative function in mitochondrial RNA turnover](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00973)
20. [Distinct Antiviral Roles for Human 2′,5′-Oligoadenylate Synthetase Family Members against Dengue Virus Infection](http://www.ebi.ac.uk/QuickGO/annotations?protein=P00973&geneProductId=UniProtKB:P00973)
21. [New susceptibility loci in MYL2, C12orf51 and OAS1 associated with 1-h plasma glucose as predisposing risk factors for type 2 diabetes in the Korean population](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00973)
22. [The p59 oligoadenylate synthetase-like protein possesses antiviral activity that requires the C-terminal ubiquitin-like domain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00973)
23. [The p59 oligoadenylate synthetase-like protein possesses antiviral activity that requires the C-terminal ubiquitin-like domain](http://www.ebi.ac.uk/QuickGO/annotations?protein=P00973&geneProductId=UniProtKB:P00973)
24. Ensembl Release 99
25. [Identifiers.org](https://registry.identifiers.org/registry/uniprot)