# 15-hydroxyprostaglandin dehydrogenase

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21121861](https://www.wikidata.org/wiki/Q21121861)  
**Source**: https://4ort.xyz/entity/15-hydroxyprostaglandin-dehydrogenase


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P15428)
3. Q20641742
4. [Threonine 188 is critical for interaction with NAD+ in human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15428)
5. [Key NAD+-binding residues in human 15-hydroxyprostaglandin dehydrogenase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15428)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15428&geneProductId=UniProtKB:P15428)
7. [Sequence of a novel mRNA coding for a C-terminal-truncated form of human NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15428&geneProductId=UniProtKB:P15428)
8. [Role of glutamine 148 of human 15-hydroxyprostaglandin dehydrogenase in catalytic oxidation of prostaglandin E2](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15428&geneProductId=UniProtKB:P15428)
9. [Key NAD+-binding residues in human 15-hydroxyprostaglandin dehydrogenase](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15428&geneProductId=UniProtKB:P15428)
10. [Site-directed mutagenesis of the conserved tyrosine 151 of human placental NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase yields a catalytically inactive enzyme](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15428&geneProductId=UniProtKB:P15428)
11. [Threonine 188 is critical for interaction with NAD+ in human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15428&geneProductId=UniProtKB:P15428)
12. [Site-directed mutagenesis of the conserved tyrosine 151 of human placental NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase yields a catalytically inactive enzyme](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15428)
13. [Role of glutamine 148 of human 15-hydroxyprostaglandin dehydrogenase in catalytic oxidation of prostaglandin E2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15428)
14. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15428)
15. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15428&geneProductId=UniProtKB:P15428)
16. [Sequence of a novel mRNA coding for a C-terminal-truncated form of human NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15428)
17. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15428)
18. [Proteomic analysis of podocyte exosome-enriched fraction from normal human urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15428&geneProductId=UniProtKB:P15428)
19. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15428&geneProductId=UniProtKB:P15428)
20. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15428)
21. [15-Hydroxyprostaglandin dehydrogenase, a COX-2 oncogene antagonist, is a TGF-beta-induced suppressor of human gastrointestinal cancers](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15428)
22. [Regulation of 15-hydroxyprostaglandin dehydrogenase (PGDH) gene activity, messenger ribonucleic acid processing, and protein abundance in the human chorion in late gestation and labor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15428)
23. [Regulation of 15-hydroxyprostaglandin dehydrogenase (PGDH) gene activity, messenger ribonucleic acid processing, and protein abundance in the human chorion in late gestation and labor](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15428&geneProductId=UniProtKB:P15428)
24. Ensembl Release 99