{"schema_version":"4ort.packet/1","entity":{"entity_id":"bone-morphogenetic-protein-15","kg_uuid":"dc1f2a2f-76be-48f2-b891-41a8b97622ef","wikidata_id":"Q22677344","name":"Bone morphogenetic protein 15","description":"mammalian protein found in Homo sapiens","type":"Protein","url":"https://4ort.xyz/entity/bone-morphogenetic-protein-15"},"status":"complete","as_of":{"copy_written_at":"2026-05-03T18:28:36Z","last_source_edit_seen":null,"stale_possible":false},"facts":[{"field":"P31","label":"instance of","value":"protein","value_id":"Q8054","value_raw":"Q8054","rank":"normal","current":null,"qualifiers":[],"layer":"source","citation":{"source":"wikidata","source_name":"Wikidata","source_record":"https://www.wikidata.org/wiki/Q22677344#P31","source_edition":"2026-05-03T18:28:36Z","edition_basis":"copy_written_at","licence":"CC0 1.0 Universal","licence_url":"https://creativecommons.org/publicdomain/zero/1.0/","attribution":null,"references":[{"stated_in":"UniProt","stated_in_id":"Q905695","retrieved":"2019-11-13"}]},"trust":{"band":"high","basis":"wikidata-reference-support/2","calibrated":false}},{"field":"P279","label":"subclass of","value":"protein","value_id":"Q8054","value_raw":"Q8054","rank":"normal","current":null,"qualifiers":[],"layer":"source","citation":{"source":"wikidata","source_name":"Wikidata","source_record":"https://www.wikidata.org/wiki/Q22677344#P279","source_edition":"2026-05-03T18:28:36Z","edition_basis":"copy_written_at","licence":"CC0 1.0 Universal","licence_url":"https://creativecommons.org/publicdomain/zero/1.0/","attribution":null,"references":[{"stated_in":"UniProt","stated_in_id":"Q905695","retrieved":"2016-12-01"}]},"trust":{"band":"high","basis":"wikidata-reference-support/2","calibrated":false}},{"field":"P361","label":"part of","value":"Cystine-knot cytokine","value_id":"Q24783539","value_raw":"Q24783539","rank":"normal","current":null,"qualifiers":[],"layer":"source","citation":{"source":"wikidata","source_name":"Wikidata","source_record":"https://www.wikidata.org/wiki/Q22677344#P361","source_edition":"2026-05-03T18:28:36Z","edition_basis":"copy_written_at","licence":"CC0 1.0 Universal","licence_url":"https://creativecommons.org/publicdomain/zero/1.0/","attribution":null,"references":[{"url":"http://www.ebi.ac.uk/interpro/protein/O95972","stated_in":"InterPro Release 71.0","stated_in_id":"Q58943792"}]},"trust":{"band":"high","basis":"wikidata-reference-support/2","calibrated":false}},{"field":"P361","label":"part of","value":"Bone morphogenetic protein 15","value_id":"Q24738729","value_raw":"Q24738729","rank":"normal","current":null,"qualifiers":[],"layer":"source","citation":{"source":"wikidata","source_name":"Wikidata","source_record":"https://www.wikidata.org/wiki/Q22677344#P361","source_edition":"2026-05-03T18:28:36Z","edition_basis":"copy_written_at","licence":"CC0 1.0 Universal","licence_url":"https://creativecommons.org/publicdomain/zero/1.0/","attribution":null,"references":[{"url":"http://www.ebi.ac.uk/interpro/protein/O95972","stated_in":"InterPro Release 71.0","stated_in_id":"Q58943792"}]},"trust":{"band":"high","basis":"wikidata-reference-support/2","calibrated":false}},{"field":"P361","label":"part of","value":"Transforming growth factor-beta, C-terminal domain, protein family","value_id":"Q83133008","value_raw":"Q83133008","rank":"normal","current":null,"qualifiers":[],"layer":"source","citation":{"source":"wikidata","source_name":"Wikidata","source_record":"https://www.wikidata.org/wiki/Q22677344#P361","source_edition":"2026-05-03T18:28:36Z","edition_basis":"copy_written_at","licence":"CC0 1.0 Universal","licence_url":"https://creativecommons.org/publicdomain/zero/1.0/","attribution":null,"references":[{}]},"trust":{"band":"medium","basis":"wikidata-reference-support/2","calibrated":false}},{"field":"P361","label":"part of","value":"Transforming growth factor beta, conserved site, protein family","value_id":"Q95353195","value_raw":"Q95353195","rank":"normal","current":null,"qualifiers":[],"layer":"source","citation":{"source":"wikidata","source_name":"Wikidata","source_record":"https://www.wikidata.org/wiki/Q22677344#P361","source_edition":"2026-05-03T18:28:36Z","edition_basis":"copy_written_at","licence":"CC0 1.0 Universal","licence_url":"https://creativecommons.org/publicdomain/zero/1.0/","attribution":null,"references":[{}]},"trust":{"band":"medium","basis":"wikidata-reference-support/2","calibrated":false}},{"field":"P352","label":"UniProt protein ID","value":"O95972","value_id":null,"value_raw":"O95972","rank":"normal","current":null,"qualifiers":[],"layer":"source","citation":{"source":"wikidata","source_name":"Wikidata","source_record":"https://www.wikidata.org/wiki/Q22677344#P352","source_edition":"2026-05-03T18:28:36Z","edition_basis":"copy_written_at","licence":"CC0 1.0 Universal","licence_url":"https://creativecommons.org/publicdomain/zero/1.0/","attribution":null,"references":[{"stated_in":"UniProt","stated_in_id":"Q905695","retrieved":"2019-11-13"}]},"trust":{"band":"high","basis":"wikidata-reference-support/2","calibrated":false}},{"field":"P527","label":"has part(s)","value":"Transforming growth factor beta, conserved site","value_id":"Q24725603","value_raw":"Q24725603","rank":"normal","current":null,"qualifiers":[],"layer":"source","citation":{"source":"wikidata","source_name":"Wikidata","source_record":"https://www.wikidata.org/wiki/Q22677344#P527","source_edition":"2026-05-03T18:28:36Z","edition_basis":"copy_written_at","licence":"CC0 1.0 Universal","licence_url":"https://creativecommons.org/publicdomain/zero/1.0/","attribution":null,"references":[{"url":"http://www.ebi.ac.uk/interpro/protein/O95972","stated_in":"InterPro Release 71.0","stated_in_id":"Q58943792"}]},"trust":{"band":"high","basis":"wikidata-reference-support/2","calibrated":false}},{"field":"P527","label":"has part(s)","value":"Transforming growth factor-beta, C-terminal","value_id":"Q24721300","value_raw":"Q24721300","rank":"normal","current":null,"qualifiers":[],"layer":"source","citation":{"source":"wikidata","source_name":"Wikidata","source_record":"https://www.wikidata.org/wiki/Q22677344#P527","source_edition":"2026-05-03T18:28:36Z","edition_basis":"copy_written_at","licence":"CC0 1.0 Universal","licence_url":"https://creativecommons.org/publicdomain/zero/1.0/","attribution":null,"references":[{"url":"http://www.ebi.ac.uk/interpro/protein/O95972","stated_in":"InterPro Release 71.0","stated_in_id":"Q58943792"}]},"trust":{"band":"high","basis":"wikidata-reference-support/2","calibrated":false}},{"field":"P637","label":"RefSeq protein ID","value":"NP_005439","value_id":null,"value_raw":"NP_005439","rank":"normal","current":null,"qualifiers":[],"layer":"source","citation":{"source":"wikidata","source_name":"Wikidata","source_record":"https://www.wikidata.org/wiki/Q22677344#P637","source_edition":"2026-05-03T18:28:36Z","edition_basis":"copy_written_at","licence":"CC0 1.0 Universal","licence_url":"https://creativecommons.org/publicdomain/zero/1.0/","attribution":null,"references":[{"stated_in":"NCBI Gene","stated_in_id":"Q20641742","retrieved":"2020-05-30"}]},"trust":{"band":"high","basis":"wikidata-reference-support/2","calibrated":false}},{"field":"P680","label":"molecular function","value":"transforming growth factor beta receptor binding","value_id":"Q14903935","value_raw":"Q14903935","rank":"normal","current":null,"qualifiers":[{"field":"P459","label":"determination method or standard","value":"IBA"}],"layer":"source","citation":{"source":"wikidata","source_name":"Wikidata","source_record":"https://www.wikidata.org/wiki/Q22677344#P680","source_edition":"2026-05-03T18:28:36Z","edition_basis":"copy_written_at","licence":"CC0 1.0 Universal","licence_url":"https://creativecommons.org/publicdomain/zero/1.0/","attribution":null,"references":[{"url":"http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95972","stated_in":"Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium","stated_in_id":"Q34211397","retrieved":"2019-04-08"}]},"trust":{"band":"high","basis":"wikidata-reference-support/2","calibrated":false}},{"field":"P680","label":"molecular function","value":"growth factor activity","value_id":"Q14820601","value_raw":"Q14820601","rank":"normal","current":null,"qualifiers":[{"field":"P459","label":"determination method or standard","value":"IEA"}],"layer":"source","citation":{"source":"wikidata","source_name":"Wikidata","source_record":"https://www.wikidata.org/wiki/Q22677344#P680","source_edition":"2026-05-03T18:28:36Z","edition_basis":"copy_written_at","licence":"CC0 1.0 Universal","licence_url":"https://creativecommons.org/publicdomain/zero/1.0/","attribution":null,"references":[{"url":"http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95972","stated_in":"GOA","stated_in_id":"Q28018111","retrieved":"2019-04-08"},{"url":"http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95972","stated_in":"GOA","stated_in_id":"Q28018111","retrieved":"2019-04-08"}]},"trust":{"band":"high","basis":"wikidata-reference-support/2","calibrated":false}},{"field":"P680","label":"molecular function","value":"cytokine activity","value_id":"Q14862699","value_raw":"Q14862699","rank":"normal","current":null,"qualifiers":[{"field":"P459","label":"determination method or standard","value":"IBA"}],"layer":"source","citation":{"source":"wikidata","source_name":"Wikidata","source_record":"https://www.wikidata.org/wiki/Q22677344#P680","source_edition":"2026-05-03T18:28:36Z","edition_basis":"copy_written_at","licence":"CC0 1.0 Universal","licence_url":"https://creativecommons.org/publicdomain/zero/1.0/","attribution":null,"references":[{"url":"http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95972","stated_in":"GOA","stated_in_id":"Q28018111","retrieved":"2019-04-08"},{"url":"http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95972","stated_in":"Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium","stated_in_id":"Q34211397","retrieved":"2019-04-08"}]},"trust":{"band":"high","basis":"wikidata-reference-support/2","calibrated":false}},{"field":"P681","label":"cell component","value":"cytoplasm","value_id":"Q79899","value_raw":"Q79899","rank":"normal","current":null,"qualifiers":[{"field":"P459","label":"determination method or standard","value":"IEA"}],"layer":"source","citation":{"source":"wikidata","source_name":"Wikidata","source_record":"https://www.wikidata.org/wiki/Q22677344#P681","source_edition":"2026-05-03T18:28:36Z","edition_basis":"copy_written_at","licence":"CC0 1.0 Universal","licence_url":"https://creativecommons.org/publicdomain/zero/1.0/","attribution":null,"references":[{"url":"http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95972","stated_in":"GOA","stated_in_id":"Q28018111","retrieved":"2019-04-08"}]},"trust":{"band":"high","basis":"wikidata-reference-support/2","calibrated":false}},{"field":"P681","label":"cell component","value":"extracellular region","value_id":"Q14645596","value_raw":"Q14645596","rank":"normal","current":null,"qualifiers":[{"field":"P459","label":"determination method or standard","value":"IEA"}],"layer":"source","citation":{"source":"wikidata","source_name":"Wikidata","source_record":"https://www.wikidata.org/wiki/Q22677344#P681","source_edition":"2026-05-03T18:28:36Z","edition_basis":"copy_written_at","licence":"CC0 1.0 Universal","licence_url":"https://creativecommons.org/publicdomain/zero/1.0/","attribution":null,"references":[{"url":"http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95972","stated_in":"GOA","stated_in_id":"Q28018111","retrieved":"2019-04-08"}]},"trust":{"band":"high","basis":"wikidata-reference-support/2","calibrated":false}},{"field":"P681","label":"cell component","value":"extracellular space","value_id":"Q1385443","value_raw":"Q1385443","rank":"normal","current":null,"qualifiers":[{"field":"P459","label":"determination method or standard","value":"IBA"}],"layer":"source","citation":{"source":"wikidata","source_name":"Wikidata","source_record":"https://www.wikidata.org/wiki/Q22677344#P681","source_edition":"2026-05-03T18:28:36Z","edition_basis":"copy_written_at","licence":"CC0 1.0 Universal","licence_url":"https://creativecommons.org/publicdomain/zero/1.0/","attribution":null,"references":[{"url":"http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95972","stated_in":"GOA","stated_in_id":"Q28018111","retrieved":"2019-04-08"},{"url":"http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95972","stated_in":"GOA","stated_in_id":"Q28018111","retrieved":"2019-04-08"}]},"trust":{"band":"high","basis":"wikidata-reference-support/2","calibrated":false}},{"field":"P681","label":"cell component","value":"endoplasmic reticulum lumen","value_id":"Q14633848","value_raw":"Q14633848","rank":"normal","current":null,"qualifiers":[{"field":"P459","label":"determination method or standard","value":"TAS"}],"layer":"source","citation":{"source":"wikidata","source_name":"Wikidata","source_record":"https://www.wikidata.org/wiki/Q22677344#P681","source_edition":"2026-05-03T18:28:36Z","edition_basis":"copy_written_at","licence":"CC0 1.0 Universal","licence_url":"https://creativecommons.org/publicdomain/zero/1.0/","attribution":null,"references":[{"url":"http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95972","stated_in":"GOA","stated_in_id":"Q28018111","retrieved":"2019-04-08"}]},"trust":{"band":"high","basis":"wikidata-reference-support/2","calibrated":false}},{"field":"P682","label":"biological process","value":"ovarian follicle development","value_id":"Q14863379","value_raw":"Q14863379","rank":"normal","current":null,"qualifiers":[{"field":"P459","label":"determination method or standard","value":"IEA"}],"layer":"source","citation":{"source":"wikidata","source_name":"Wikidata","source_record":"https://www.wikidata.org/wiki/Q22677344#P682","source_edition":"2026-05-03T18:28:36Z","edition_basis":"copy_written_at","licence":"CC0 1.0 Universal","licence_url":"https://creativecommons.org/publicdomain/zero/1.0/","attribution":null,"references":[{"url":"http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95972","stated_in":"GOA","stated_in_id":"Q28018111","retrieved":"2019-04-08"}]},"trust":{"band":"high","basis":"wikidata-reference-support/2","calibrated":false}},{"field":"P682","label":"biological process","value":"female gamete generation","value_id":"Q14872802","value_raw":"Q14872802","rank":"normal","current":null,"qualifiers":[{"field":"P459","label":"determination method or standard","value":"TAS"}],"layer":"source","citation":{"source":"wikidata","source_name":"Wikidata","source_record":"https://www.wikidata.org/wiki/Q22677344#P682","source_edition":"2026-05-03T18:28:36Z","edition_basis":"copy_written_at","licence":"CC0 1.0 Universal","licence_url":"https://creativecommons.org/publicdomain/zero/1.0/","attribution":null,"references":[{"url":"http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95972","stated_in":"The bone morphogenetic protein 15 gene is X-linked and expressed in oocytes","stated_in_id":"Q22008525","retrieved":"2019-04-08"}]},"trust":{"band":"high","basis":"wikidata-reference-support/2","calibrated":false}},{"field":"P682","label":"biological process","value":"positive regulation of pathway-restricted SMAD protein phosphorylation","value_id":"Q14903088","value_raw":"Q14903088","rank":"normal","current":null,"qualifiers":[{"field":"P459","label":"determination method or standard","value":"IBA"}],"layer":"source","citation":{"source":"wikidata","source_name":"Wikidata","source_record":"https://www.wikidata.org/wiki/Q22677344#P682","source_edition":"2026-05-03T18:28:36Z","edition_basis":"copy_written_at","licence":"CC0 1.0 Universal","licence_url":"https://creativecommons.org/publicdomain/zero/1.0/","attribution":null,"references":[{"url":"http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95972","stated_in":"Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium","stated_in_id":"Q34211397","retrieved":"2019-04-08"}]},"trust":{"band":"high","basis":"wikidata-reference-support/2","calibrated":false}},{"field":"P682","label":"biological process","value":"BMP signaling pathway","value_id":"Q14864806","value_raw":"Q14864806","rank":"normal","current":null,"qualifiers":[{"field":"P459","label":"determination method or standard","value":"IBA"}],"layer":"source","citation":{"source":"wikidata","source_name":"Wikidata","source_record":"https://www.wikidata.org/wiki/Q22677344#P682","source_edition":"2026-05-03T18:28:36Z","edition_basis":"copy_written_at","licence":"CC0 1.0 Universal","licence_url":"https://creativecommons.org/publicdomain/zero/1.0/","attribution":null,"references":[{"url":"http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95972","stated_in":"Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium","stated_in_id":"Q34211397","retrieved":"2019-04-08"}]},"trust":{"band":"high","basis":"wikidata-reference-support/2","calibrated":false}},{"field":"P682","label":"biological process","value":"regulation of apoptotic process","value_id":"Q14633911","value_raw":"Q14633911","rank":"normal","current":null,"qualifiers":[{"field":"P459","label":"determination method or standard","value":"IBA"}],"layer":"source","citation":{"source":"wikidata","source_name":"Wikidata","source_record":"https://www.wikidata.org/wiki/Q22677344#P682","source_edition":"2026-05-03T18:28:36Z","edition_basis":"copy_written_at","licence":"CC0 1.0 Universal","licence_url":"https://creativecommons.org/publicdomain/zero/1.0/","attribution":null,"references":[{"url":"http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95972","stated_in":"Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium","stated_in_id":"Q34211397","retrieved":"2019-04-08"}]},"trust":{"band":"high","basis":"wikidata-reference-support/2","calibrated":false}},{"field":"P702","label":"encoded by","value":"BMP15","value_id":"Q14903582","value_raw":"Q14903582","rank":"normal","current":null,"qualifiers":[],"layer":"source","citation":{"source":"wikidata","source_name":"Wikidata","source_record":"https://www.wikidata.org/wiki/Q22677344#P702","source_edition":"2026-05-03T18:28:36Z","edition_basis":"copy_written_at","licence":"CC0 1.0 Universal","licence_url":"https://creativecommons.org/publicdomain/zero/1.0/","attribution":null,"references":[{"stated_in":"UniProt","stated_in_id":"Q905695","retrieved":"2019-11-13"}]},"trust":{"band":"high","basis":"wikidata-reference-support/2","calibrated":false}},{"field":"P703","label":"found in taxon","value":"Homo sapiens","value_id":"Q15978631","value_raw":"Q15978631","rank":"normal","current":null,"qualifiers":[],"layer":"source","citation":{"source":"wikidata","source_name":"Wikidata","source_record":"https://www.wikidata.org/wiki/Q22677344#P703","source_edition":"2026-05-03T18:28:36Z","edition_basis":"copy_written_at","licence":"CC0 1.0 Universal","licence_url":"https://creativecommons.org/publicdomain/zero/1.0/","attribution":null,"references":[{"stated_in":"UniProt","stated_in_id":"Q905695","retrieved":"2019-11-13"}]},"trust":{"band":"high","basis":"wikidata-reference-support/2","calibrated":false}},{"field":"P705","label":"Ensembl protein ID","value":"ENSP00000252677","value_id":null,"value_raw":"ENSP00000252677","rank":"normal","current":null,"qualifiers":[],"layer":"source","citation":{"source":"wikidata","source_name":"Wikidata","source_record":"https://www.wikidata.org/wiki/Q22677344#P705","source_edition":"2026-05-03T18:28:36Z","edition_basis":"copy_written_at","licence":"CC0 1.0 Universal","licence_url":"https://creativecommons.org/publicdomain/zero/1.0/","attribution":null,"references":[{"stated_in":"Ensembl Release 99","stated_in_id":"Q83867711"}]},"trust":{"band":"high","basis":"wikidata-reference-support/2","calibrated":false}}],"unknowns":[],"omitted":{"facts":0,"reason":null},"licences":[{"source":"wikidata","source_name":"Wikidata","licence":"CC0 1.0 Universal","licence_url":"https://creativecommons.org/publicdomain/zero/1.0/","attribution":null,"fields":["P31","P279","P361","P352","P527","P637","P680","P681","P682","P702","P703","P705"]}],"routes":{"entity_page":"https://4ort.xyz/entity/bone-morphogenetic-protein-15","packet_api":"https://4ort.xyz/api/v1/entities/bone-morphogenetic-protein-15/packet","facts_jsonld":"https://4ort.xyz/entity/bone-morphogenetic-protein-15/facts.json","changes_api":"https://4ort.xyz/api/v1/knowledge/get_entity_changes?entity=bone-morphogenetic-protein-15","attention_api":"https://4ort.xyz/api/v1/knowledge/get_attention?entity=bone-morphogenetic-protein-15","wikidata":"https://www.wikidata.org/wiki/Q22677344","official_website":null},"trust_rules":{"wikidata-reference-support/2":"From the references in our copy of the statement: high = it cites a source (stated in P248, or a reference URL that is not Wikipedia); medium = only 'imported from Wikimedia project' or a Wikipedia URL; unscored = our copy holds no reference (older copies dropped references, so this is not evidence that Wikidata has none). Wikidata may hold more references than our copy shows. Reference support, not a probability."},"notes":[]}